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52

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
T14057 6-CFDA

6-羧基荧光素二醋酸,6-Carboxyfluorescein diacetate

Others Others
6-CFDA (6-Carboxyfluorescein diacetate) 是可用于流式细胞术和荧光显微镜的荧光探针,也可以用于活体多光子显微镜研究动物肝胆代谢。
T18894 5(6)-CFDA

CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯

Others Others
5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) 是具有细胞渗透性的胺反应型绿色荧光探针(λex: 492 nm; λem: 517 nm),可用于细胞染色分析。
T18896 5(6)-FITC

Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate

Others Others
5(6)-FITC (Fluorescein isothiocyanate), or Fluorescein 5(6)-isothiocyanate, is a versatile amine-reactive derivative of fluorescein dye. It serves as an effective label for antibodies and other probes, finding utility in fluorescence microscopy, flow cytometry, and immunofluorescence-based assays such as ELISA and Western blotting.
T77767L1 GLF16 HCl

Others Others
GLF16 HCl 是一种荧光团偶联的苏丹黑 B 类似物,可通过通过荧光显微镜和流式细胞术快速检测、分离和实时跟踪衰老细胞。
T78393 C12FDG

5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside

C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) 作为一种亲脂性用于检测β-半乳糖活性的绿色荧光底物,是一种衰老标志物,常与流式细胞仪连用。
T36958 BODIPY 505/515

BODIPY 505/515 是一种亲脂性荧光探针,可定位到细胞内的脂质体,已被用于标记脂滴。BODIPY 505/515 已被用于电子显微镜、外荧光显微镜、共聚焦显微镜以及各种藻类物种的流式细胞仪应用中。
T15609 JC-1

CBIC2

Others Others
JC-1 (CBIC2) 是一种荧光亲脂性羰花青染料,用于测量线粒体膜电位。线粒体膜电位较高时,它在基质中汇聚形成聚合物,可以产生红色荧光(λex=585 nm,λem=590 nm)。线粒体膜电位较低时,它不能聚集在线粒体基质中,以单体形式存在产生绿色荧光(λex=510 nm,λem=527 nm)。
T4433 6-CFDA N-succinimidyl ester

Carboxyfluorescein diacetate succinimidyl

Others Others
6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) 能够自发且不可逆地与游离胺结合。在流式细胞术实验中用于追踪哺乳动物细胞和细菌的细胞分裂。与多种细胞透化剂结合使用,作为一种有效的、非破坏性的荧光染料,可快速检测细菌细胞。
T2130 Propidium Iodide

PI,碘化丙啶,碘化丙啶(PI)

Others Others
Propidium Iodide (PI) 是一种可用于细胞染色的红色荧光染料,适用于荧光显微镜、共聚焦显微镜、流式细胞仪以及荧光计分析。在水溶液中,Propidium Iodide 的Ex/Em 为493/636 nm;与核酸结合后,PI-核酸的Ex/Em 变为535/617 nm,同时荧光信号增强20-30倍。
T14058 6-FITC

6-异硫氰酸荧光素,6-Fluorescein Isothiocyanate

Others Others
6-Fluorescein Isothiocyanate (6-FITC) is a fluorescein derivative widely employed in applications such as flow cytometry.
T39027 PKH 26

PKH 26 is a lipophilic membrane dye and widely used to determine cell proliferation in heterogeneous cells by flow cytometry. It is a red‐fluorescent dye (Ex/Em=551/567nm).
T37317 Fluo-3 (sodium salt)

Fluo-3 is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T37316 Fluo-3 (potassium salt)

Fluo-3 (potassium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T18989 Fluo-3AM

Fluo-3-pentaacetoxymethyl ester

Others Others
Fluo-3AM is a calcium indicator that exhibits an increase in fluorescence upon binding Ca2+. It is used to image the spatial dynamics of Ca2+ signaling in flow cytometry experiments.
T39546 Fluorescein tyramide

Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.
T37315 Fluo-3 (ammonium salt)

Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. [1] Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T77767L GLF16 FA

GLF16 FA 是一种亲水性荧光 SBB 类似物,可使用流式细胞术和活细胞分选来快速检测衰老细胞。
TP1960 (D)-PPA 1

PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
TD0053 Fluo-3, pentapotassium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentapotassium salt is most commonly used among the visible light-excitable calcium indicators.
TD0052 Fluo-3, pentasodium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentasodium salt is most commonly used among the visible light-excitable calcium indicators.
TD0054 Fluo-3, pentaammonium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentaammonium salt is most commonly used among the visible light-excitable calcium indicators.
T78089 FITC-labeled ODN 1018 sodium

FITC-labeled ODN 1018 (sodium) 作为TLR9激动剂,其细胞内摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行评估。
T37090 Indo-1 (potassium salt)

Indo-1 (potassium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (potassium salt) binds calcium. Indo-1 (potassium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.
TD0021 Super Fluor 488

Super Fluor 488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 488 dye is pH-insensitive over a wide molar range.Probes with high fluo
TD0025 Super Fluor 647

Super Fluor 647 dye is a bright, far-red–fluorescent dye with excitation ideally suited for the 594 nm or 633 nm laser lines. For stable signal generation in imaging and flow cytometry, Super Fluor 647 dye is pH-insensitive over a wide molar range.Probes
T37091 Indo-1 (sodium salt)

Indo-1 (sodium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (sodium salt) binds calcium. Indo-1 (sodium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.
T75334 Methyl Green

Methyl Green 为有效荧光染料,用于细胞与电泳凝胶DNA染色,能通过显微镜与流式细胞术直接测定活性,活性峰值位于633及677 nm。储存应避光。
T78996 FITC-labeled ODN 2088 sodium

FITC-labeled ODN 2088 (sodium) 作为TLR3、TLR7和TLR9的抑制剂,可用于评估CpG ODN在细胞内的摄取与定位。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行检测。
T78663 FITC-labeled Agatolimod sodium

FITC-labeled Agatolimod (sodium) 是一种B类CpG ODN,兼具TLR9激动剂功能。该化合物应用共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可以评估CpG ODN在细胞内的摄取及定位情况。
TD0027 Super Fluor 680

Super Fluor 680 dye is a bright, near-IR fluorescent dye with excitation ideally suited for the 633 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 680 dye is pH-insensitive over a wide molar range.The fluorescence q
T78998 FITC-labeled ODN 2216 sodium

FITC-labeled ODN 2216 (sodium) 为TLR9激动剂,其细胞摄取与定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术评估。
T78992 FITC-labeled ODN 1585 sodium

FITC-labeled ODN 1585 (sodium) 为B类CpG ODN同时兼作TLR9激动剂。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可评估其细胞内摄取和定位情况。
T36369 3,6-diacetoxy Phthalonitrile

3,6-diacetoxy Phthalonitrile is a fluorescent probe for monitoring intracellular pH by flow cytometry in living cells. It rapidly crosses cell membranes and is cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH), which is excited at UV wavelengths. DCH can be excited at 351 nm, with pH-dependent emission in the range of 450-476 nm (pH 5.0-10.0) using a potassium-based buffer.
T78665 FITC-labeled ODN 1826 sodium

FITC-labeled ODN 1826(sodium)为B类CpG ODN,兼作TLR9激动剂。该化合物的细胞摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)及流式细胞术进行评估。
TD0050 Fluo-4, pentapotassium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentapotassium salt is an analog of fluo-3 with th...
T79000 FITC-labeled ODN 2395 sodium

FITC-labeled ODN 2395 (sodium) 是C类CpG ODN,具有TLR9激动剂功能。该化合物的细胞摄取和定位可通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术进行评估。
T82496 eGFP circRNA-LNP

eGFP circRNA-LNP 是一种含有eGFP circRNA 的脂质纳米粒,可用于RNA传递、翻译效率和细胞活力检测。该eGFP circRNA包括增强型绿色荧光蛋白标签,为细胞内绿色荧光蛋白的表达提供基础,且eGFP作为报告基因,可通过荧光显微镜或流式细胞术进行检测。
TD0049 Fluo-4, pentasodium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentasodium salt is an analog of fluo-3 with the t...
T82388 Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Caspase Apoptosis; Proteases/Proteasome
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone 是一种细胞渗透性且无毒的抑制剂,它能与活化的caspase-3在凋亡细胞内不可逆结合。该抑制剂的荧光强度可通过流式细胞仪、微孔板读数器或荧光显微镜检测。
T82494 eGFP mRNA-LNP

eGFP mRNA-LNP 是一种蕴含eGFP mRNA 的脂质纳米粒,应用于RNA传递、翻译效率及细胞活力的测定。eGFP circRNA携带eGFP以实现绿色荧光蛋白表达,此蛋白可经由荧光显微镜或流式细胞术进行检测,充当报告基因。
T78994 FITC-labeled ODN 1668 sodium

FITC-labeled ODN 1668 (sodium) 是B类CpG ODN,兼具TLR9激动剂功能。该化合物能借助共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)及流式细胞术,用于评估CpG ODN在细胞内的摄取及定位情况。
T73604 Methyl Green zinc chloride

Methyl Green zinc chloride为高效荧光染料,主要用于细胞DNA及电泳凝胶染色。该化合物能直接通过显微镜及流式细胞术进行活性测定,其活性峰值位于633至677 nm。储存应避光。
T79002 FITC-labeled ODN TTAGGG sodium

FITC-labeled ODN TTAGGG (sodium) 作为一种寡核苷酸抑制剂,对TLR9、AIM2及cGAS具有拮抗作用。通过共聚焦激光扫描显微镜(激发/发射光波长:495/520 nm)或流式细胞术,可以评估CpG ODN在细胞内的摄取及定位情况。
T30783 CDy9

CDy 9,CDy-9

CDy9 is a highly selective fluorescent probe for the detection and isolation of mESC using fluorescence microscopy and flow cytometry. CDy9 allows the detection and isolation of intact stem cells with marginal impact on their function and capabilities. CD
TD0051 Fluo-4, pentaammonium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentaammonium salt is an analog of fluo-3 with the...
T37040 DiIC1(5)

DiIC1(5)

DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption. It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potential is disrupted. DilC1(5) has been used in combination with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry. It has also been used as a quencher for the detection of serine phosphorylation and tyrosine dephosphorylation p...
TD0029 Super Fluor 750

Super Fluor 750 dye is a bright, near-IR–fluorescent dye with excitation ideally suited for the 633 nm laser line or dye-pumped laser excitation. Super Fluor 750 dye is pH-insensitive over a wide molar range, helping ensure that you get stable signals in
T77767 GLF16

GLF16 是一种亲水性荧光 SBB 类似物,可有效识别衰老。 它可以使用流式细胞术和活细胞分选来快速检测衰老细胞。 GLF16 适用于各种生物材料中单细胞水平的衰老细胞群的体内鉴定、分离和下游表征。
T82391 Fluo-3

Fluo-3及其相关化合物Fluo3/AM作为细胞内钙(Ca2+)的荧光指示剂。Fluo-3可用于可见光激发(与波长为488 nm的氩离子激光光源兼容)的流式细胞术和共聚焦激光扫描显微镜研究。与钙结合后,荧光强度可增加约40倍。
T83959 CELT-426

CELT-426是一种高效且部分选择性的荧光hD2多巴胺受体拮抗剂,其Kivalue分别针对D2、D3和D4多巴胺受体,在放射配体结合实验中分别为89.3 nM、194.8 nM和263.6 nM。CELT-426可作为荧光多巴胺受体探针,在荧光结合实验、活细胞成像、流式细胞术及荧光偏振实验中使用。它是GPCR放射性标记配体的理想替代品。激发和发射峰值(λ)分别为560 nm和571 nm。这些波长适合作为TR-FRET实验中的受体染料,与CoraFluor1 TR-FRET供体一起使用。

化合物

6-CFDA
Cat.No: T14057
Synonym: 6-羧基荧光素二醋酸,6-Carboxyfluorescein diacetate
Target: Others
5(6)-CFDA
Cat.No: T18894
Synonym: CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯
Target: Others
5(6)-FITC
Cat.No: T18896
Synonym: Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate
Target: Others
GLF16 HCl
Cat.No: T77767L1
Synonym:
Target: Others
C12FDG
Cat.No: T78393
Synonym: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
Target:
BODIPY 505/515
Cat.No: T36958
Synonym:
Target:
JC-1
Cat.No: T15609
Synonym: CBIC2
Target: Others
6-CFDA N-succinimidyl ester
Cat.No: T4433
Synonym: Carboxyfluorescein diacetate succinimidyl
Target: Others
Propidium Iodide
Cat.No: T2130
Synonym: PI,碘化丙啶,碘化丙啶(PI)
Target: Others
6-FITC
Cat.No: T14058
Synonym: 6-异硫氰酸荧光素,6-Fluorescein Isothiocyanate
Target: Others
PKH 26
Cat.No: T39027
Synonym:
Target:
Fluo-3 (sodium salt)
Cat.No: T37317
Synonym:
Target:
Fluo-3 (potassium salt)
Cat.No: T37316
Synonym:
Target:
Fluo-3AM
Cat.No: T18989
Synonym: Fluo-3-pentaacetoxymethyl ester
Target: Others
Fluorescein tyramide
Cat.No: T39546
Synonym:
Target:
Fluo-3 (ammonium salt)
Cat.No: T37315
Synonym:
Target:
GLF16 FA
Cat.No: T77767L
Synonym:
Target:
(D)-PPA 1
Cat.No: TP1960
Synonym:
Target:
Fluo-3, pentapotassium salt
Cat.No: TD0053
Synonym:
Target:
Fluo-3, pentasodium salt
Cat.No: TD0052
Synonym:
Target:
Fluo-3, pentaammonium salt
Cat.No: TD0054
Synonym:
Target:
FITC-labeled ODN 1018 sodium
Cat.No: T78089
Synonym:
Target:
Indo-1 (potassium salt)
Cat.No: T37090
Synonym:
Target:
Super Fluor 488
Cat.No: TD0021
Synonym:
Target:
Super Fluor 647
Cat.No: TD0025
Synonym:
Target:
Indo-1 (sodium salt)
Cat.No: T37091
Synonym:
Target:
Methyl Green
Cat.No: T75334
Synonym:
Target:
FITC-labeled ODN 2088 sodium
Cat.No: T78996
Synonym:
Target:
FITC-labeled Agatolimod sodium
Cat.No: T78663
Synonym:
Target:
Super Fluor 680
Cat.No: TD0027
Synonym:
Target:
FITC-labeled ODN 2216 sodium
Cat.No: T78998
Synonym:
Target:
FITC-labeled ODN 1585 sodium
Cat.No: T78992
Synonym:
Target:
3,6-diacetoxy Phthalonitrile
Cat.No: T36369
Synonym:
Target:
FITC-labeled ODN 1826 sodium
Cat.No: T78665
Synonym:
Target:
Fluo-4, pentapotassium salt
Cat.No: TD0050
Synonym:
Target:
FITC-labeled ODN 2395 sodium
Cat.No: T79000
Synonym:
Target:
eGFP circRNA-LNP
Cat.No: T82496
Synonym:
Target:
Fluo-4, pentasodium salt
Cat.No: TD0049
Synonym:
Target:
Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone
Cat.No: T82388
Synonym:
Target: Caspase
eGFP mRNA-LNP
Cat.No: T82494
Synonym:
Target:
FITC-labeled ODN 1668 sodium
Cat.No: T78994
Synonym:
Target:
Methyl Green zinc chloride
Cat.No: T73604
Synonym:
Target:
FITC-labeled ODN TTAGGG sodium
Cat.No: T79002
Synonym:
Target:
CDy9
Cat.No: T30783
Synonym: CDy 9,CDy-9
Target:
Fluo-4, pentaammonium salt
Cat.No: TD0051
Synonym:
Target:
DiIC1(5)
Cat.No: T37040
Synonym: DiIC1(5)
Target:
Super Fluor 750
Cat.No: TD0029
Synonym:
Target:
GLF16
Cat.No: T77767
Synonym:
Target:
Fluo-3
Cat.No: T82391
Synonym:
Target:
CELT-426
Cat.No: T83959
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1328 7-Amino-4-methylcoumarin-3-acetic acid

7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin

Others Others
7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂,能够被紫外光(350 nm) 激活,可在蓝色区域 (440-460 nm) 发光。

天然产物

7-Amino-4-methylcoumarin-3-acetic acid
Cat.No: TN1328
Synonym: 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin
Target: Others
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