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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T11427	Antibacterial compound 2	Antifungal	Microbiology/Virology
	Antibacterial compound 2 是一种有效的抗菌剂，对许多人类兽医病原体有效，对多重耐药葡萄球菌、肠球菌和链球菌，以及厌氧菌有抑制作用。
T23639	Adicillin NSC113137,NSC 113137,NSC-113137
	Adicillin is a penicillin antibiotic that works against vancomycin-resistant enterococci.
T37881	Oritavancin(LY-333328)
	Oritavancin is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci.
T38125	Platencin
	Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis, which is also the source of platensimycin . Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic resistant bacterial strains, including ...
T74821	Nemonoxacin
	Nemonoxacin (TG-873870) 是一种口服有效的广谱抗生素，对多种葡萄球菌、链球菌、肠球菌、淋病奈瑟菌和流感嗜血杆菌显示出强效的抑制活性。适用于研究细菌感染和社区获得性肺炎。
T73600	Cefaloglycin
	Cefaloglycin（Cephaloglycin）是一种β-内酰胺类（β-lactam）口服活性头孢菌素类抗生素，具有肾毒性和抗菌活性。该药物对革兰氏阳性球菌（除肠球菌外）有效，同时对线粒体底物摄取及呼吸具有毒性。
T38009	Kocurin
	Kocurin is a thiazolyl peptide originally isolated fromK. palustrisand has antibiotic activity.1It is active against methicillin-resistantS. aureus(MRSA; MIC = 0.25 μg/ml), as well asB. subtilisandE. faeciumin a solid agar test when used at a concentration of 8 μg/ml. Kocurin is also active againstE. faecium,E. faecalis,S. epidermidis, and clinical isolates of vancomycin-resistant enterococci (MICs = 0.004-1.025 μg/ml).2In vivo, kocurin (2.5, 5, and 10 mg/ml) increases survival in a mouse model ...
T14359	AVX 13616	Others	Others
	AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin i

化合物

Antibacterial compound 2

Cat.No: T11427

Synonym:

Target: Antifungal

Adicillin

Cat.No: T23639

Synonym: NSC113137,NSC 113137,NSC-113137

Target:

Oritavancin(LY-333328)

Cat. No.	Product Name	Target	Signaling Pathways
T3982	Vulpinic Acid 狐衣酸,Vulpic acid,Pulvinic acid methyl ester	Others	Others
	Vulpinic Acid (Pulvinic acid methyl ester) 是地衣代谢物，可降低人脐静脉内皮细胞 (HUVEC) 中 H2O2诱导的ROS，氧化应激和氧化应激相关损伤，可作用于厌氧菌、葡萄球菌及肠球菌。它对脉粥样硬化的研究具有潜在的价值。
T0832	Vancomycin hydrochloride 盐酸万古霉素,Vancomycin HCl	Cell wall; Antibacterial; Antibiotic; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology
	Vancomycin hydrochloride (Vancomycin HCl) 是Vancomycin 的盐酸盐，是一种支链三环糖基化肽，对大多数生物体具有杀菌活性，对肠球菌具有抑菌作用。
TN1342	8-Epidiosbulbin E acetate 8-表黄药子素E乙酸酯	Anti-infection; Antibacterial	Microbiology/Virology
	8-Epidiosbulbin E acetate 是从 Dioscorea bulbifera L.中发现的呋喃类化合物，对耐多药细菌具有广谱的质粒治疗活性。
TN4148	Glyasperin C	Tyrosinase; Antifection	Microbiology/Virology; Proteases/Proteasome
	Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. Glyasperin C shows potent anti-vancomycin-resistant