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Cat. No.	Product Name	Target	Signaling Pathways
T3468	Tomivosertib eFT508	MNK; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK
	Tomivosertib (eFT508) 是一种具有口服活性的MNK1和MNK2高选择性抑制剂，IC50值均为 1-2 nM。它可降低肿瘤细胞中eIF4E 的磷酸化水平 (位点为 Ser209，IC50=2-16 nM)，下调PD-L1蛋白的平均含量。
T70123	N-5984 Hydrochloride
	N-5984 Hydrochloride is a beta3-AR agonist.
T70124	Tomivosertib HCl
	Tomivosertib, also known as eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.