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13

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T40670	7-Deaza-7-propargylamino-dATP
	7-Deaza-7-propargylamino-dATP is a deoxyadenosine triphosphate (dATP) analog utilized in the field of gene sequencing.
T40774	7-Deaza-7-propargylamino-3'-azidomethyl-dATP
	7-Deaza-7-propargylamino-3'-azidomethyl-dATP, an analog of deoxyadenosine triphosphate (dATP), finds extensive utilization in next-generation sequencing (NGS).
T75384	Cy5-dATP
	Cy5-dATP 是Cy5 标记的dATP。Cy5-dATP 可以掺入 DNA 引物中。
T83829	2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium ε-dATP
	ε-dATP是一种具有荧光性的嘌呤核苷酸2’-脱氧腺苷-5’-O-三磷酸（dATP）衍生物。它能在50至150µM的浓度范围内诱导初级小鼠脾脏T细胞和B细胞在脂多糖(LPS)或刀豆蛋白A刺激下发生姊妹染色单体交换。ε-dATP已被用于研究乙烯氯诱导的突变过程中模糊碱基配对的情况。相关的ATP衍生物ε-ATP，在300 nm激发下显示415 nm的发射峰值。
T83830	2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium 2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP
	2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate是ATP的一种氟代衍生物，ATP是细胞代谢必需的能量底物。它抑制E. coli RNA聚合酶(Ki = 200 µM)。
T74398	DATPT	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	DATPT 是一种小分子 12WLVSKF17 肽模拟分子。DATPT 抑制 SNX9-p47phox 相互作用，抑制活性氧和炎性细胞因子的产生。DATPT 具有抗炎和抗菌活性，通过减少 ATP 的产生发挥作用。DATPT 是治疗脓毒症的潜在化合物。
T10982	ddATP 2',3'-Dideoxyadenosine 5'-triphosphate	Others	Others
	ddATP is a dideoxynucleotide, used as a chain extension inhibitor for DNA polymerase, and used for DNA sequencing by the Sanger method.
T38532	7-Deaza-7-propargylamino-ddATP
	7-Deaza-7-propargylamino-ddATP, an analog of ddATP, serves as a viable option for gene sequencing purposes due to its chemical composition.
T60217	TAS1553	Others	Others
	TAS1553是一种高效的可口服蛋白质-蛋白质相互作用(PPI)抑制剂，其IC50值为0.0396 μM。TAS1553 有效地阻碍DNA复制并减少细胞内dATP池。此外，TAS1553诱导凋亡，[1]使其在癌症研究中极具价值。
T6501	Fludarabine Phosphate NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP,磷酸氟达拉滨	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Fludarabine Phosphate (NSC 312887 Phosphate) 是一种腺苷和脱氧腺苷类似物，与 dATP 竞争，并入到 DNA，可以抑制 DNA 聚合酶 α、核糖核苷酸还原酶和 DNA 引发酶，从而中断 DNA 合成并抑制肿瘤细胞生长。
T37910	Tenofovir diphosphate triethylamine
	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1].
T37909	Tenofovir diphosphate
	Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1].
T37106	2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
	2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations ...

化合物

7-Deaza-7-propargylamino-dATP

Cat.No: T40670

7-Deaza-7-propargylamino-3'-azidomethyl-dATP

Cat.No: T40774

Cat.No: T75384

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium

Cat.No: T83829

Synonym: ε-dATP

2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium

Cat.No: T83830

Synonym: 2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP

Cat.No: T74398

Target: Reactive Oxygen Species, Antibacterial

Cat.No: T10982

Synonym: 2',3'-Dideoxyadenosine 5'-triphosphate

Target: Others

7-Deaza-7-propargylamino-ddATP

Cat.No: T38532

Cat.No: T60217

Target: Others

Fludarabine Phosphate

Cat.No: T6501

Synonym: NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP,磷酸氟达拉滨

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Tenofovir diphosphate triethylamine

Cat.No: T37910

Tenofovir diphosphate

Cat.No: T37909

2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)

Cat.No: T37106

Cat. No.	Product Name	Target	Signaling Pathways
T37635	2'-Deoxyadenosine-5'-triphosphate trisodium dATP trisodium	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸，是 DNA 聚合酶的底物，在细胞中用于 DNA 合成或复制。
T36667	2'-Deoxyadenosine-5'-triphosphate dATP,Deoxyadenosine 5-triphosphate	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸，在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-Deoxyadenosine-5'-triphosphate 通过无活性的 α4beta4 四级结构抑制RNA。2'-Deoxyadenosine-5'-triphosphate 与心肌细胞生长有关。

天然产物

2'-Deoxyadenosine-5'-triphosphate trisodium

Cat.No: T37635

Synonym: dATP trisodium

Target: DNA/RNA Synthesis, Endogenous Metabolite

2'-Deoxyadenosine-5'-triphosphate

Cat.No: T36667

Synonym: dATP,Deoxyadenosine 5-triphosphate

Target: DNA/RNA Synthesis, Endogenous Metabolite

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