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7

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
T21419 Diphenhydramine

苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Diphenhydramine (Syntedril) 是第一代具有抗胆碱能作用的H1 受体拮抗剂,它能透过血脑屏障。
T0205 Brompheniramine maleate

Dimotane,马来酸溴苯那敏,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane

5-HT Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Brompheniramine maleate (Dimotane) 是一种可口服的丙胺类抗组胺剂,具有抗胆碱能和抗抑郁作用,可用于过敏性鼻炎和缓解疼痛的研究。它是一种选择性组胺 H1 受体拮抗剂,Kd 为 6.06 nM。
T0464 Carbetapentane citrate

托可拉斯,Pentoxyverine citrate,咳必清

AChR Neuroscience
Carbetapentane citrate (Pentoxyverine citrate) 能够选择性抑制咳嗽中枢,具有轻度的阿托品样作用和局麻作用。
T4563 Thonzylamine

neohetramine,松齐拉敏

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂,具有抗组胺和抗过敏特性,可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T1232 Mepyramine maleate

马来酸吡纳明,Pyrilamine maleate,吡拉明马来酸盐

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mepyramine maleate (Pyrilamine maleate) 是一种组胺 H1 拮抗剂,对 H1、H2 和 H3 受体的 Kd 值分别为 0.8、5200 和大于 3000 nM,对 H1 受体的 pKd 值为 9.4。它是感冒药的常见成分,具有温和的催眠特性和局部麻醉作用,可用于胃肠外和局部过敏。
T33978 Phenindamine Tartrate

Pernovine,Thephorin,Nolahist,Phenindamine,Plegine

Phenindamine Tartrate is an antihistamine and anticholinergic drug closely related to cyproheptadine. It is used to treat symptoms of the common cold and allergies, such as sneezing, itching, rashes, and hives.
T71286 Guaifenesin-d3

Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing ...

化合物

Diphenhydramine
Cat.No: T21419
Synonym: 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255
Target: Histamine Receptor
Brompheniramine maleate
Cat.No: T0205
Synonym: Dimotane,马来酸溴苯那敏,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane
Target: 5-HT Receptor, Histamine Receptor
Carbetapentane citrate
Cat.No: T0464
Synonym: 托可拉斯,Pentoxyverine citrate,咳必清
Target: AChR
Thonzylamine
Cat.No: T4563
Synonym: neohetramine,松齐拉敏
Target: Histamine Receptor
Mepyramine maleate
Cat.No: T1232
Synonym: 马来酸吡纳明,Pyrilamine maleate,吡拉明马来酸盐
Target: Histamine Receptor
Phenindamine Tartrate
Cat.No: T33978
Synonym: Pernovine,Thephorin,Nolahist,Phenindamine,Plegine
Target:
Guaifenesin-d3
Cat.No: T71286
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0330 Diphenhydramine hydrochloride

盐酸苯海拉明,Diphenhydramine HCl,DPH

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Diphenhydramine hydrochloride (DPH) 是一种组胺 H1 拮抗剂,用作镇咳药和止吐药。它还用于治疗瘙痒和皮肤病、过敏反应、抗帕金森病、催眠药和普通感冒制剂的成分。

天然产物

Diphenhydramine hydrochloride
Cat.No: T0330
Synonym: 盐酸苯海拉明,Diphenhydramine HCl,DPH
Target: Histamine Receptor
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