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Search Results for " beta-lactam "

40

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14979	Clavulanate lithium Clavulanic acid lithium,克拉维酸锂	Antibacterial	Microbiology/Virology
	Clavulanate lithium (Clavulanic acid lithium) 是一种β-lactamase 的高效抑制剂，可作抗生素。
T6622	Oxacillin sodium monohydrate 苯唑西林钠一水合物,Stapenor monohydrate,苯唑青霉素钠,Sodium oxacillin monohydrate,Methicillin,Bactocill monohydrate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Oxacillin sodium monohydrate (Stapenor monohydrate) 是一种抗生素，可研究耐药性葡萄球菌感染，类似 Flucloxacillin。
T1495	Cefaclor monohydrate Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor	Antibacterial; Antibiotic	Microbiology/Virology
	Cefaclor monohydrate (Cefaclorum) 是一种抗生素，可特异性地结合青霉素结合蛋白。
T0234	Methicillin sodium salt Methicillin sodium,Meticillin sodium,甲氧西林钠	Antibacterial; Antibiotic	Microbiology/Virology
	Methicillin sodium salt 是β-内酰胺抗生素，抑制参与肽聚糖合成的青霉素结合蛋白。
T1631	Sulbactam CP45899,舒巴坦,舒巴坦酸	Antibacterial; Antibiotic	Microbiology/Virology
	Sulbactam (CP45899) 是一种竞争性、不可逆的 β-内酰胺酶抑制剂，抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。
T5570	Cephalothin 头孢噻吩,Cephalotin acid	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalothin 是一种 β-内酰胺抗生素，抑制 C 类 β-内酰胺酶活性的 Ki 值为 0.32 µM。
T6438	Cefoselis Sulfate FK 037 Sulfate,FK-037,硫酸头孢噻利	Antibacterial; Antibiotic	Microbiology/Virology
	Cefoselis Sulfate (FK 037 Sulfate) 是一种头孢菌素 β-内酰胺抗生素。它对多种革兰氏阳性和革兰氏阴性生物均表现出良好的活性。它可以透过血脑屏障。
T5024	Cefotiam Hexetil Hydrochloride 盐酸头孢替安酯,头孢替安海替酯盐酸盐	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotiam hexetil hydrochloride 是一种可口服头孢菌素，是抗生素 cefotiam 的前药，但无抗菌作用。
T6582	Mezlocillin Sodium 美洛西林钠,Baycipen	Antibacterial; Antibiotic	Microbiology/Virology
	Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素，用于治疗由易感染微生物引起的细菌感染。
T1305	Ceftazidime GR20263,头孢他啶	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftazidime (GR20263) 是可静脉内或肌肉给药的第头孢菌素。它对革兰氏阳性和革兰氏阴性需氧细菌有体外活性。它对肠杆菌科特别有效，对大多数 β-内酰胺酶具有抗水解作用。
T11265	Faropenem daloxate 法罗培南酯,Faropenem medoxil	Antibacterial; Antibiotic	Microbiology/Virology
	Faropenem daloxate (Faropenem medoxil) 是β-内酰胺类口服抗生素。
T19860	Clavulanic Acid BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151	Antibacterial; Antifungal	Microbiology/Virology
	Clavulanic Acid(RX-10100) 是一种由生物体克拉维链霉菌产生的主要β-内酰胺类抗生素，是一种强效的细菌 β-内酰胺酶抑制剂，用于研究细菌引起的感染。Clavulanic Acid 具有广谱的生物活性，对多种革兰氏阳性和革兰氏阴性细菌均有活性。
T0199	Cephradine Anspor,Cephradin,Velosef,SQ-11436,Sefril,头孢拉定	TOPK; Antibacterial; Antibiotic	MAPK; Microbiology/Virology
	Cephradine (Anspor) 是广谱口服活性头孢菌素。它对革兰氏阳性和革兰氏阴性病原体都有活性。它已用于泌尿生殖系统、胃肠道和呼吸道感染以及皮肤和软组织感染的研究。它通过直接抑制TOPK 抑制太阳紫外线诱导的皮肤炎症。
T1616	Cefotiam hydrochloride 盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotiam hydrochloride (SCE-963 hydrochloride) 是一种肠外头孢菌素类广谱抗生素，对革兰氏阳性菌和革兰氏阴性菌有活性。
T0932	Cefixime FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635	Antibacterial; Antibiotic	Microbiology/Virology
	Cefixime (FR-17027) 是一种头孢菌素类抗生素, 可研究一些细菌感染。
T0953	Cefazolin sodium Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefazolin sodium (cephazolin sodium) salt 是一种头孢类抗生素, 可研究多种细菌感染。
T1063	Ticarcillin disodium Ticarpen,Ticarcillin disodium salt,替卡西林二钠	Antibacterial; Antibiotic	Microbiology/Virology
	Ticarcillin disodium (Ticarpen) 主要用于抗革兰氏阴性菌, 特别是绿脓杆菌, 也是少数可研究嗜麦芽感染的抗生素。
T1122	Cephalothin sodium 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性，抑制革兰氏阳性和阴性菌。
T24180	Isosulfazecin
	Isosulfazecin is a beta-lactam antibiotic.
T25659	Lenampicillin Lenampicilina
	Lenampicillin is a Beta-lactam antibacterial agent.
T32456	L 652813 L652813,L-652813
	L 652813 is one kind of quaternary heterocyclylamino beta-lactam.
T28725	SCH34343 sodium SCH34343,SCH-34343,SCH 34343
	SCH34343 is a beta-lactam antibiotic.
T23882	Chitinovorin B
	Chitinovorin B is a beta-lactam antibiotic.
T22642	Cefoselis hydrochloride	Others	Others
	Cefoselis is a widely used beta-lactam antibiotic.
T26153	RU 44790 RU-44790,RU44790
	RU 44790 is a synthetic monocyclic beta-lactam antibiotics.
T34768	Tabtoxin
	Tabtoxin is a dipeptide containing tabtoxinine-beta-lactam with threonine.
T25597	Lactivicin
	Lactivicin is a non-beta-lactam antibiotic that acts by binding to penicillin-binding proteins.
T69300	AVE-1330A free acid
	AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.
T24328	L 680833 L680,833,L680833,L-680,833,L 680,833,L-680833
	L 680833 is an orally active monocyclic beta-lactam human polymorphonuclear leukocyte elastase inhibitor.
T25183	Bulgecin C
	Bulgecin C is an O-sulfonated glycopeptides that can enhance the antibacterial activity of beta-lactam antibiotics.
T75391	Penicillinase
	Penicillinase 是一种 β-内酰胺酶。β-内酰胺酶通过水解特征性四元 β-内酰胺环的肽键使抗生素失效，从而使 β-内酰胺抗生素失活。
T21440	Nafcillin Unipen,Nallpen
	Nafcillin sodium, a narrow-spectrum beta-lactam antibiotic of the penicillin class, is used to treat infections caused by Gram-positive bacteria, in particular, species of staphylococci that are resistant to other penicillins.
T21384	Dicloxacillin Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen
	Dicloxacillin (INN), a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins.
T15734	Lenampicillin hydrochloride 盐酸仑氨苄西林,KBT 1585 hydrochloride	Antibacterial	Microbiology/Virology
	Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin
T33359	Meticillin Staphcillin,Methicillin,Dimethoxyphenyl Penicillin,Metin
	Methicillin is a narrow-spectrum beta-lactam antibiotic of the penicillin-like family, used to treat infections caused by susceptible gram-positive bacteria, in particular penicillase-producing organisms such as Staphylococcus aureus.
T14492	BAL-30072	Others	Others
	BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli
T38458	Faropenem
	Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory...
T74378	Temocillin
	Temocillin为6-α-甲氧基青霉素衍生物，为半合成β-内酰胺类抗生素，对多数需氧革兰氏阴性菌展现特定抗菌活性。
T69873	Cefdinir monohydrate
	Cefdinir monohydrate is the salt form of Cefdinir (free base), a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidog...
T65598	Cefminox sodium
	Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ...

化合物

Clavulanate lithium

Cat.No: T14979

Synonym: Clavulanic acid lithium,克拉维酸锂

Target: Antibacterial

Oxacillin sodium monohydrate

Cat.No: T6622

Synonym: 苯唑西林钠一水合物,Stapenor monohydrate,苯唑青霉素钠,Sodium oxacillin monohydrate,Methicillin,Bactocill monohydrate

Target: Others, Antibacterial, Antibiotic

Cefaclor monohydrate

Cat.No: T1495

Synonym: Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor

Target: Antibacterial, Antibiotic

Methicillin sodium salt

Cat.No: T0234

Synonym: Methicillin sodium,Meticillin sodium,甲氧西林钠

Target: Antibacterial, Antibiotic

Cat.No: T1631

Synonym: CP45899,舒巴坦,舒巴坦酸

Target: Antibacterial, Antibiotic

Cat.No: T5570

Synonym: 头孢噻吩,Cephalotin acid

Target: Antibacterial, Antibiotic

Cefoselis Sulfate

Cat.No: T6438

Synonym: FK 037 Sulfate,FK-037,硫酸头孢噻利

Target: Antibacterial, Antibiotic

Cefotiam Hexetil Hydrochloride

Cat.No: T5024

Synonym: 盐酸头孢替安酯,头孢替安海替酯盐酸盐

Target: Antibacterial, Antibiotic

Mezlocillin Sodium

Cat.No: T6582

Synonym: 美洛西林钠,Baycipen

Target: Antibacterial, Antibiotic

Cat.No: T1305

Synonym: GR20263,头孢他啶

Target: Antibacterial, Antibiotic

Faropenem daloxate

Cat.No: T11265

Synonym: 法罗培南酯,Faropenem medoxil

Target: Antibacterial, Antibiotic

Clavulanic Acid

Cat.No: T19860

Synonym: BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151

Target: Antibacterial, Antifungal

Cat.No: T0199

Synonym: Anspor,Cephradin,Velosef,SQ-11436,Sefril,头孢拉定

Target: TOPK, Antibacterial, Antibiotic

Cefotiam hydrochloride

Cat.No: T1616

Synonym: 盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor

Target: Antibacterial, Antibiotic

Cat.No: T0932

Synonym: FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635

Target: Antibacterial, Antibiotic

Cefazolin sodium

Cat.No: T0953

Synonym: Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin

Target: Others, Antibacterial, Antibiotic

Ticarcillin disodium

Cat.No: T1063

Synonym: Ticarpen,Ticarcillin disodium salt,替卡西林二钠

Target: Antibacterial, Antibiotic

Cephalothin sodium

Cat.No: T1122

Synonym: 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin

Target: Antibacterial, Antibiotic

Cat.No: T24180

Cat.No: T25659

Synonym: Lenampicilina

Cat.No: T32456

Synonym: L652813,L-652813

SCH34343 sodium

Cat.No: T28725

Synonym: SCH34343,SCH-34343,SCH 34343

Cat.No: T23882

Cefoselis hydrochloride

Cat.No: T22642

Target: Others

Cat.No: T26153

Synonym: RU-44790,RU44790

Cat.No: T34768

Cat.No: T25597

AVE-1330A free acid

Cat.No: T69300

Cat.No: T24328

Synonym: L680,833,L680833,L-680,833,L 680,833,L-680833

Cat.No: T25183

Cat.No: T75391

Cat.No: T21440

Synonym: Unipen,Nallpen

Cat.No: T21384

Synonym: Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen

Lenampicillin hydrochloride

Cat.No: T15734

Synonym: 盐酸仑氨苄西林,KBT 1585 hydrochloride

Target: Antibacterial

Cat.No: T33359

Synonym: Staphcillin,Methicillin,Dimethoxyphenyl Penicillin,Metin

Cat.No: T14492

Target: Others

Cat.No: T38458

Cat.No: T74378

Cefdinir monohydrate

Cat.No: T69873

Cefminox sodium

Cat.No: T65598

Cat. No.	Product Name	Target	Signaling Pathways
T1029	Aztreonam SQ-26,776,氨曲南	Antibacterial; Antibiotic	Microbiology/Virology
	Aztreonam (SQ-26,776) 是单环β-内酰胺抗生素，与青霉素结合蛋白3有较高亲和力。
T1505	Imipenem monohydrate N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物	Antibacterial; Antibiotic	Microbiology/Virology
	Imipenem monohydrate (Imipenem) 是从微生物 Streptomyces cattleya 分离得到的碳青霉烯类抗生素，是一种用于静脉注射的β 内酰胺类抗生素，作用于细菌细胞壁，能广泛有效抑制多种革兰氏阳性和阴性菌。

天然产物

Cat.No: T1029

Synonym: SQ-26,776,氨曲南

Target: Antibacterial, Antibiotic

Imipenem monohydrate

Cat.No: T1505

Synonym: N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物

Target: Antibacterial, Antibiotic

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