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Cat. No. Product Name Target Signaling Pathways
TP1359L Amyloid β Peptide (42-1)(human) acetate

Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Beta Amyloid Neuroscience
Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽,其在阿尔茨海默病的发病机制中起关键作用。
T35499 β-Amyloid (1-42), (rat/mouse) (TFA)

Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA

β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段,可用于研究阿尔茨海默症。
T32106 Human beta-amyloid protein 42 (1-7)

Vanutide

Human beta-amyloid protein 42 (1-7) is a bioactive chemical.
TP1359 β-Amyloid (42-1), human

Amyloid β Peptide (42-1)(human)

β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.
TP1007 β-Amyloid (1-42), human

大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Beta Amyloid Neuroscience
β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽,在阿尔茨海默病的发病机制中起关键作用。
T38149 β-Amyloid (1-43)(human)

The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.
T37768 β-Amyloid (1-37) (human)

β-Amyloid (1-37) (human) 与阿尔茨海默病的精神状态有潜在关联。
T37370 Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM....
T77042 Aducanumab

BIIB037

Beta Amyloid Neuroscience
Aducanumab (BIIB037),一种选择性人免疫球蛋白γ-1(IgG1)单克隆抗体,靶向β淀粉样蛋白 (Aβ) 的聚集形式。Aducanumab 显示出脑渗透性,可用于治疗阿尔茨海默病 (AD) 。
T13253 Umibecestat

CNP520

BACE Neuroscience
Umibecestat 是一种β-位点淀粉样前体蛋白裂解酶-1 (BACE-1) 抑制剂,对人 BACE-1 和小鼠 BACE-1 的 IC50 分别为 11 nM 和 10 nM,可用于阿尔茨海默病的研究。
T31828 AZD4694

Flutafuranol,AZD 4694,NAV-4694,AZD-4694,NAV 4694,NAV4694

Flutafuranol, also known as AZD 4694 and NAV4694, is a bio-active chemical. AZD4694 shows high affinity for beta-amyloid fibrils in vitro (K(d) = 2.3 +/- 0.3 nM). The fluorine-18 labeled AZD4694 may have potential for PET-visualization of cerebral beta-am
T80701 β Amyloid (1-16) rat

β-Amyloid (1-16) rat 是β-淀粉样肽 (Abeta) 金属结合域的片段,含有三个与人类相异的氨基酸替代,因此在大鼠和小鼠中降低了 AD 样神经退行性变的易感性。
T82242 hAChE-IN-6

hAChE-IN-6(化合物51)是一种能够穿透血脑屏障的AChE抑制剂,具有0.16 μM的IC50。该化合物同时对hBuChE与GSK3β显示出抑制活性,其IC50分别为0.69 μM和0.26 μM。hAChE-IN-6亦能抑制tau蛋白与Aβ1-42的自聚集,适用于阿尔茨海默病(AD)的相关研究。
T82243 hAChE-IN-5

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
hAChE-IN-5(化合物49)是一种同时针对hAChE和hBuChE的有效抑制剂,其IC50值均为0.17 μM。此外,hAChE-IN-5对GSK3β同样展现出良好的抑制活性,IC50值为0.21 μM。作为tau蛋白聚集和Aβ1-42自聚集的抑制剂,hAChE-IN-5能够结合PAS,进而阻止Aβ依赖的神经毒性。其能穿透血脑屏障(BBB),显示出成为多靶点抗阿尔茨海默病药物研究的潜力。

化合物

Amyloid β Peptide (42-1)(human) acetate
Cat.No: TP1359L
Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)
Target: Beta Amyloid
β-Amyloid (1-42), (rat/mouse) (TFA)
Cat.No: T35499
Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
Target:
Human beta-amyloid protein 42 (1-7)
Cat.No: T32106
Synonym: Vanutide
Target:
β-Amyloid (42-1), human
Cat.No: TP1359
Synonym: Amyloid β Peptide (42-1)(human)
Target:
β-Amyloid (1-42), human
Cat.No: TP1007
Synonym: 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human
Target: Beta Amyloid
β-Amyloid (1-43)(human)
Cat.No: T38149
Synonym:
Target:
β-Amyloid (1-37) (human)
Cat.No: T37768
Synonym:
Target:
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
Cat.No: T37370
Synonym:
Target:
Aducanumab
Cat.No: T77042
Synonym: BIIB037
Target: Beta Amyloid
Umibecestat
Cat.No: T13253
Synonym: CNP520
Target: BACE
AZD4694
Cat.No: T31828
Synonym: Flutafuranol,AZD 4694,NAV-4694,AZD-4694,NAV 4694,NAV4694
Target:
β Amyloid (1-16) rat
Cat.No: T80701
Synonym:
Target:
hAChE-IN-6
Cat.No: T82242
Synonym:
Target:
hAChE-IN-5
Cat.No: T82243
Synonym:
Target: GSK-3
TargetMol Loading
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