Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0046 |
Bavisant
JNJ-31001074 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Bavisant (JNJ-31001074) 是一种特异性和口服活性的人 H3 受体拮抗剂。 Bavisant 可用于作用机制的研究,包括觉醒和认知以及 ADHD 的治疗。 | |||
T2150 |
Guanfacine hydrochloride
盐酸胍法辛,Tenex,Intuniv,Guanfacine |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Guanfacine hydrochloride (Intuniv) 是一种 α2A 肾上腺素受体激动剂,Kd=31 nM,具有抗高血压作用。 | |||
T60201 |
CX717
|
GluR | Neuroscience |
CX 717 是 AMPA 受体的正变构调节剂,具有抗抑郁样作用。CX 717 可用于成人注意力缺陷多动障碍(ADHD)的研究。 | |||
T31604 |
Edivoxetine
LY-2216684,LY 2216684,LY2216684 |
||
Edivoxetine( LY2216684) is a selective norepinephrine reuptake inhibitor being developed as a treatment for attention deficit hyperactivity disorder (ADHD) and antidepressants. | |||
T10226 |
Sofiniclin
ABT 894 |
Others | Others |
Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD). | |||
T60369 |
Droxidopa hydrochloride
|
||
Droxidopa (L-DOPS) hydrochloride 是一种有效的、具有口服活性的去甲肾上腺素前体。Droxidopa hydrochloride 可增加站立血压,改善直立性低血压症状并提高站立能力。Droxidopa hydrochloride 具有研究神经源性直立性低血压(nOH)和替代性多动症 (注意缺陷多动障碍) 的潜力[3]。 | |||
T35591 |
Guanfacine-13C,15N3
Guanfacine-13C,15N3 |
||
Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin... |