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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T31482	Diloxanide Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida,二氯尼特	Parasite	Microbiology/Virology
	Diloxanide (RD3803) 是一种抗原虫制剂，可研究组织学内阿米巴原虫或者其他原虫感染引起的无症状肠道阿米巴病。它是一种活性的鲁米那抗阿米巴试剂，是由其前药二氯尼特糠酸酯在胃肠道中水解得来的。
T63409	Teclozan
	Teclozan 是一种苄胺衍生物类的抗原虫剂。Teclozan 在肠腔中表现出抗 G. intestinalis 作用，能够干预磷脂代谢，阻止花生四烯酸的形成。Teclozan 能够用于研究原生动物感染。
T35747	Quinacrine analog 34
	Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels ...
T80377	Xenopsin precursor fragment	Parasite	Microbiology/Virology
	Xenopsin precursor fragment 为抗菌肽，展现抗菌/抗真菌(MIC: 10-500 μg/mL)及抗原虫(MIC: 2-20 μg/mL)效能。
T23210	Quinacrine (dihydrochloride hydrate) Quinacrine (hydrochloride hydrate) (83-89-6 free base)	Others	Others
	Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM） and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 μM). As an e
T69117	Pinafide
	Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD⁺-dependent DNA ligase A at concentrations ...

化合物

Diloxanide

Cat.No: T31482

Synonym: Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida,二氯尼特

Xenopsin precursor fragment

Cat.No: T80377

Synonym:

Target: Parasite

Quinacrine (dihydrochloride hydrate)

Cat.No: T23210

Synonym: Quinacrine (hydrochloride hydrate) (83-89-6 free base)

Cat. No.	Product Name	Target	Signaling Pathways
TN3644	Chlorophorin	Tyrosinase; Antifection	Microbiology/Virology; Proteases/Proteasome
	Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM; it inhibits α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.