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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T25437	Fpl 14294 Fpl-14294,Fpl14294
	Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.
T28823	SNAP-7941 SNAP7941
	SNAP-7941 is a selective antagonist of the melanin concentrating hormone receptor MCH1 with promising anxiolytic, antidepressant and anorectic effects in initial animal studies.
T24801	SKF-77434, (S)- S-(-)-Apd,J482.833J,S-(-)-SKF-77434
	SKF-77,434 is a drug that acts as a selective dopamine D1 receptor partial agonist. It also has stimulant and anorectic effects.
T29103	VER-3323 VER3323,Lopac-V-1889,Lopac V-1889
	VER-3323 is a selective agonist for the 5-HT2B and 5-HT2C serotonin receptor with potent anorectic effects in animal studies.
T27550	HMR-1426 HMR 1426,HMR1426
	HMR-1426 is gastric emptying inhibitor. HMR1426 shows an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure or behavior.
T35631	Peptide YY (human) (trifluoroacetate salt) Peptide Tyrosine Tyrosine
	Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation. PYY is cleaved in vivo to PYY (3-36) . Release of PYY occurs postprandially in proportion to calorie intake from intestinal enteroendocrine L cells, indicating it may be a satiety signal. In humans, PYY inhibits food intake and gastrointestinal transit in...
T1519L	Rimonabant SR141716,利莫那班	Cannabinoid Receptor; Antibacterial; Acyltransferase	GPCR/G Protein; Metabolism; Microbiology/Virology
	Rimonabant (SR141716) 是一种选择性的、能透过血脑屏障的中心大麻素受体 1 拮抗剂， Ki 值为 1.8 nM。它也能够抑制分枝杆菌膜蛋白 3。

化合物

Fpl 14294

Cat.No: T25437

Synonym: Fpl-14294,Fpl14294

Target:

SNAP-7941

Cat.No: T28823

Synonym: SNAP7941

Target:

SKF-77434, (S)-

Cat.No: T24801

Synonym: S-(-)-Apd,J482.833J,S-(-)-SKF-77434

Target:

VER-3323

Cat.No: T29103

Synonym: VER3323,Lopac-V-1889,Lopac V-1889

Target:

HMR-1426

Cat.No: T27550

Synonym: HMR 1426,HMR1426

Target:

Peptide YY (human) (trifluoroacetate salt)

Cat.No: T35631

Synonym: Peptide Tyrosine Tyrosine

Target:

Rimonabant

Cat.No: T1519L

Synonym: SR141716,利莫那班

Target: Cannabinoid Receptor, Antibacterial, Acyltransferase

Cat. No.	Product Name	Target	Signaling Pathways
TN5283	L-Cysteine hydrochloride hydrate L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐一水合物	Others; Endogenous Metabolite	Metabolism; Others
	L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) 是条件必需氨基酸，是硫化氢、谷胱甘肽和牛磺酸等生物活性分子的前体。它可以抑制胃饥饿素，抑制啮齿动物和人类的食欲。
T16285	Neosolaniol	Potassium Channel	Membrane transporter/Ion channel
	Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.