首页工具

登录

搜索结果

Search Results for " angioedema "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T11885	LSP-249	Others	Others
	LSP-249是血浆 kallikrein 的抑制剂，用于血管性水肿的研究，EC50值小于 100 nM。
T14358	Avoralstat BCX4161	Others	Others
	Avoralstat (BCX4161) 是血浆激肽释放酶(PKK)抑制剂，具有口服活性，可用于遗传性血管性水肿的研究。
T22344	Icatibant Acetate	Bradykinin Receptor	GPCR/G Protein
	Icatibant acetate 是一种特异性缓激肽 B2 受体拮抗剂，其 IC50=1.07 nM，Ki=0.798 nM。
T77018	Garadacimab CSL312	Factor Xa	Metabolism
	Garadacimab (CSL312) 是有效的全人 IgG4 单克隆抗体，针对活化因子 XII (FXIIa)。Garadacimab 可用于研究遗传性血管性水肿。。
T1470	Fexofenadine hydrochloride Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,盐酸非索非那定,Telfast,Fexofenadine HCl,Allegra,MDL 16455A	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) 是一种抗组胺药，用于治疗过敏性鼻炎、血管性水肿和慢性荨麻疹。
TP1792L	KKI-5 acetate(97145-43-2 free base)	Serine Protease	Proteases/Proteasome
	KKI-5 acetate(97145-43-2 free base) 是一种丝氨酸蛋白酶抑制剂，可抑制激肽释放酶和纤溶酶。 KKI 5 可能表现出抗癌化疗益处，也可用作血管性水肿的治疗方法。
TP1792	KKI-5
	KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T61403	Plasma kallikrein-IN-3
	Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1].
T21247	Carbinoxamine Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine
	Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an H1-antagonist.
T78572	Ecallantide DX-88
	Ecallantide (DX-88) 是高特异性重组血浆激肽释放酶抑制剂，用于阻断缓激肽生成，治疗血管性水肿急性发作。
T76710	Lanadelumab
	Lanadelumab (SHP643) 是一种针对血浆激肽释放酶 (plasma kallikrein (pKal)) 的人源化IgG1单克隆抗体，Ki 值为 0.12 nM。Lanadelumab 抑制游离和 HMWK 结合的 pKal。Lanadelumab 具有研究遗传性血管性水肿的潜力
T72337	Plasma kallikrein-IN-2
	Plasma kallikrein-IN-2 是一个有效的 plasma kallikrein (PKal)抑制剂，IC50值为 0.1 nM。Plasma kallikrein-IN-2 可用于遗传性血管水肿、糖尿病性黄斑水肿、糖尿病视网膜病变的研究。
T82510	Ecallantide TFA DX-88 TFA
	Ecallantide (DX-88) TFA 是一种特异性的重组血浆激肽释放酶(Kallikrein)抑制剂，作用于缓激肽的生成过程以减少其产生。此化合物主要用于预防和治疗血管性水肿的急性攻击。
T35869	Berotralstat
	Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein, which is responsible for the release of bradykinin. This blocking mechanism targets the major biologic peptide involved in the promotion of swelling and pain associated with HAE attacks[1][2].

化合物

Cat.No: T11885

Target: Others

Cat.No: T14358

Synonym: BCX4161

Target: Others

Icatibant Acetate

Cat.No: T22344

Target: Bradykinin Receptor

Cat.No: T77018

Synonym: CSL312

Target: Factor Xa

Fexofenadine hydrochloride

Cat.No: T1470

Synonym: Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,盐酸非索非那定,Telfast,Fexofenadine HCl,Allegra,MDL 16455A

Target: Histamine Receptor

KKI-5 acetate(97145-43-2 free base)

Cat.No: TP1792L

Target: Serine Protease

Cat.No: TP1792

Plasma kallikrein-IN-3

Cat.No: T61403

Cat.No: T21247

Synonym: Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine

Cat.No: T78572

Synonym: DX-88

Cat.No: T76710

Plasma kallikrein-IN-2

Cat.No: T72337

Ecallantide TFA

Cat.No: T82510

Synonym: DX-88 TFA

Cat.No: T35869

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼