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15

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T18895	5(6)-FAM SE 5(6)-羧基荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein N-hydroxysuccinimide ester	Others	Others
	5(6)-FAM SE (5(6)-Carboxyfluorescein N-hydroxysuccinimide ester) 是绿色荧光染料，普遍用于标记蛋白质。
T18967	Dansyl chloride 丹酰氯,丹磺酰氯,DNSCl	Others	Others
	Dansyl chloride (DNSC-l) 是一种能够在脂族和芳族胺与伯氨基反应，并产生稳定蓝色或蓝绿色荧光磺酰胺加合物的试剂，广泛用于修饰氨基酸、蛋白质测序和氨基酸分析。
T20161	Lauroyl alanine Lauroylalanine,N-Lauroyl-L-alanine,Aminiosurfact LA
	Lauroyl alanine is a fatty acid amide. It may be used to support the physical gelation of binary mixtures of aliphatic and aromatic hydrocarbon solvents.
T20530	Cycloate HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063
	Cycloate is a herbicide. It inhibits the biosynthesis of very-long-chain fatty acids, which is the essential constituents of plant suberin and waxes. Fatty acids also serve as precursors of aliphatic carbon chains in resorcinolic lipids.
T29489	9-Decen-2-one Dec-9-en-2-one
	9-Decen-2-one is an aliphatic ketone. It has been identified as one of the volatile components present in the normal cork samples and in the cork samples infected with Armillaria mellea and by molds. It is also present in the fresh pineapple fruits (Ananas comosus).
T38466	4-APC hydrobromide
	4-APC hydrobromide is a potent and specific aldehyde derivatization agent. It contains an aniline moiety that enables rapid and selective reaction with aliphatic aldehydes, as well as a quaternary ammonium group that enhances sensitivity in mass spectrometry (MS) analysis. By utilizing 4-APC hydrobromide, aldehydes can be detected with exceptional sensitivity and selectivity using MS.
T36240	AP219
	AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion.
T76202	Recombinant Proteinase K
	Recombinant Proteinase K为一种serine protease，专门裂解脂肪族及芳香族氨基酸的羧基端肽键，适用于蛋白质消化与清除核酸制剂中的污染。
T60299	MurA-IN-2
	MurA-IN-2 (compound 37) 是一种含有伯胺的氯乙酰胺片段，它是一种有效的 MurA 抑制剂，其 IC50值为 39 μM。MurA-IN-2 具有抗菌活性，抑制细菌细胞壁合成。
T83919	Hydroxy Darunavir R-426857
	Hydroxy darunavir是HIV-1蛋白酶抑制剂darunavir的一种代谢产物，通过异丁基脂肪族羟基化作用从darunavir形成。
T29336	2-Bromo-1-decanal Decanal-1-14C, 2-bromo-, (R)-,2-Bromo(1-14C)-1-decanal
	2-Bromo-1-decanal was synthesized as an affinity labeling probe for the aliphatic aldehyde site of Vibrio harveyi luciferase. In the presence of excess amounts of this probe, the inactivation of bacterial luciferase occurred following apparent first order
T76168	Carboxypeptidase C
	CarboxypeptidaseC为生化研究中常用的羧肽酶，专门用于切除多肽链羧基末端的赖氨酸、精氨酸和脯氨酸，同时也能处理包含中性、脂肪族、芳香族及酸性蛋白质氨基酸的肽链。
T35860	AP39
	AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP39 (30-300 nM) dose-dependently increases H2S levels in endothelial cells, predominantly in mitochondrial regions. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an i...
T37293	CMPI hydrochloride
	Potent positive allosteric modulator of α4β2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for hα4β2 over hα3β2, hα3β4 and hα7. Inhibits (α4)2(β2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 μM, respectively), but not (α4)3(β2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains. Hamouda (2016) Photolabeling a nicotinic acetylcholine receptor (nAChR) with an (α4)3(β2)2 nAChR-selective p...
T71385	Aroplatin
	Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. After displacement of the 2 long-chain aliphatic leaving groups (neodecanoic acid), platinum diaminocyclohexane (DACH) complexes become highly reactive and alkylate macromolecules, forming both inter- and intra-strand DNA crosslinks and inhibiting DNA synthesis, which results in tumor cell cytotox...

化合物

Cat.No: T18895

Synonym: 5(6)-羧基荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein N-hydroxysuccinimide ester

Target: Others

Dansyl chloride

Cat.No: T18967

Synonym: 丹酰氯,丹磺酰氯,DNSCl

Target: Others

Lauroyl alanine

Cat.No: T20161

Synonym: Lauroylalanine,N-Lauroyl-L-alanine,Aminiosurfact LA

Cat.No: T20530

Synonym: HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063

Cat.No: T29489

Synonym: Dec-9-en-2-one

4-APC hydrobromide

Cat.No: T38466

Cat.No: T36240

Recombinant Proteinase K

Cat.No: T76202

Cat.No: T60299

Hydroxy Darunavir

Cat.No: T83919

Synonym: R-426857

2-Bromo-1-decanal

Cat.No: T29336

Synonym: Decanal-1-14C, 2-bromo-, (R)-,2-Bromo(1-14C)-1-decanal

Carboxypeptidase C

Cat.No: T76168

Cat.No: T35860

CMPI hydrochloride

Cat.No: T37293

Cat.No: T71385

Cat. No.	Product Name	Target	Signaling Pathways
T2S2104	Sinigrin hydrate 黑芥子苷,Sinigrin monohydrate,芥子甙单水合物,Allylglucosinolate monohydrate	Antibacterial	Microbiology/Virology
	Sinigrin hydrate (Allylglucosinolate monohydrate) 是一种天然脂肪族芥子油苷，存在于十字花科植物中。它具有消炎、抗癌、抗真菌、抗菌、抗氧化作用。
T5261	(E)-Oct-2-enoic acid trans-2-Octenoic acid,2-Octenoate,2-辛烯酸,2-Octenoic acid	Others; Endogenous Metabolite	Metabolism; Others
	(E)-Oct-2-enoic acid (2-Octenoate) 是内源性代谢产物的一种。
T8030	Ethyl pyruvate	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Ethyl pyruvate 是一种内源性代谢物丙酮酸的衍生物，是一种抗炎剂。
T3761	1-Octacosanol n-Octacosanol,二十八烷醇,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol	Others	Others
	1-Octacosanol (Octanosol) 是直链脂肪族 28 碳脂肪醇，具有抗疲劳作用。
T0063	L-Isoleucine 异亮氨酸,isoleucine,Ile,L-异亮氨酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	L-Isoleucine (Ile) 是一种非极性疏水性氨基酸。它是必需氨基酸。
T8032	4-Pentenoic acid	Others; Endogenous Metabolite	Metabolism; Others
	4-Pentenoic acid 是内源性代谢产物的一种。
T7998	1,7-Diaminoheptane	Others	Others
	1,7-Diaminoheptane 是一种脂族胺家族的化合物。它可用于合成肽、拟肽和其他化合物，也被用作酶反应中的底物，金属配合物中的配体，以及有机合成中的试剂。
T0884	1-Docosanol Behenic alcohol,Behenyl alcohol,n-Docosanol,二十二醇,Docosanol	Antifection; HSV	Microbiology/Virology
	1-Docosanol (Behenic alcohol) 是一种具有抗病毒活性的饱和 22 碳脂肪醇，局部用于治疗复发性单纯性唇疱疹发作并缓解相关疼痛并可能有助于更快地治愈疮。
T5619	(±)-1,2-Propanediol 1,2-Propanediol,Propylene glycol,1,2-Dihydroxypropane,Methyl ethyl glycol,丙二醇	Others	Others
	(±)-1,2-Propanediol 是一种脂肪族醇，具有多种作用，可作为防腐剂和防冻剂，在食品工业和护肤品行业应用广泛。 (±)-1,2-Propanediol 是一种天然抑菌剂，能够在一定程度上抑制细菌的生长和繁殖
T3339	Sophoridine 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	Sophoridine (Dihydro-5-episophocarpine) 是一种从豆科植物槐豆斜生植物的叶子中分离出来的喹喔啉生物碱。它是胰腺癌的候选药物，诱导细胞凋亡。
T8098	γ-Hexalactone γ-caprolactone,gamma-己内酯,γ-己内酯	Others	Others
	γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤，可用作对氧磷酶 1 的底物 (PON1)。
T83464	11-(Methylsulfinyl)undecyl-glucosinolate
	11-(Methylsulfinyl)undecyl-glucosinolate 是一条长链脂肪族的硫代葡萄糖苷化合物。
T82304	Glucobrassicanapin potassium 4-Pentenylglucosinolate potassium
	Glucobrassicanapin (4-Pentenylglucosinolate) potassium 是脂肪族硫代葡萄糖苷类化合物，主要存在于白菜等蔬菜作物中。
T31471	Dihydroisoalantolactone
	Dihydroisoalantolactone is found in herbs and spices. Dihydroisoalantolactone is isolated from roots of Inula helenium (elecampane). This compound Aliphatic heteropolycyclic, belongs to the class of organic compounds known as eudesmanolides, secoeudesmano
T75549	(2E,4E)-Decadienoic acid
	(2E,4E)-Decadienoic acid 是一种抗卵菌脂肪族化合物，存在于 Bacillus subtilis 和 Trichoderma asperellum 的共培养物中。

天然产物

Sinigrin hydrate

Cat.No: T2S2104

Synonym: 黑芥子苷,Sinigrin monohydrate,芥子甙单水合物,Allylglucosinolate monohydrate

Target: Antibacterial

(E)-Oct-2-enoic acid

Cat.No: T5261

Synonym: trans-2-Octenoic acid,2-Octenoate,2-辛烯酸,2-Octenoic acid

Target: Others, Endogenous Metabolite

Cat.No: T8030

Target: Apoptosis, Antioxidant

Cat.No: T3761

Synonym: n-Octacosanol,二十八烷醇,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol

Target: Others

Cat.No: T0063

Synonym: 异亮氨酸,isoleucine,Ile,L-异亮氨酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

4-Pentenoic acid

Cat.No: T8032

Target: Others, Endogenous Metabolite

1,7-Diaminoheptane

Cat.No: T7998

Target: Others

Cat.No: T0884

Synonym: Behenic alcohol,Behenyl alcohol,n-Docosanol,二十二醇,Docosanol

Target: Antifection, HSV

(±)-1,2-Propanediol

Cat.No: T5619

Synonym: 1,2-Propanediol,Propylene glycol,1,2-Dihydroxypropane,Methyl ethyl glycol,丙二醇

Target: Others

Cat.No: T3339

Synonym: 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine

Target: Apoptosis, Topoisomerase

Cat.No: T8098

Synonym: γ-caprolactone,gamma-己内酯,γ-己内酯

Target: Others

11-(Methylsulfinyl)undecyl-glucosinolate

Cat.No: T83464

Glucobrassicanapin potassium

Cat.No: T82304

Synonym: 4-Pentenylglucosinolate potassium

Dihydroisoalantolactone

Cat.No: T31471

(2E,4E)-Decadienoic acid

Cat.No: T75549

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