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Cat. No. | Product Name | Target | Signaling Pathways |
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T0992 |
Carbenoxolone disodium
Biogastrone,Duogastrone,甘珀酸钠,Bioral |
Gap Junction Protein | Cytoskeletal Signaling |
Carbenoxolone disodium (Duogastrone) 是甘草酸的活性代谢物和人11β-HSD 和细菌3α, 20β-HSD 的抑制剂。它是一种缝隙连接的解耦剂,可抑制牛痘病毒生长,用于消化性、食道和口腔溃疡和炎症的相关研究。 | |||
T61651 |
Quinoprazine
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Quinoprazine, a powerful inhibitor of Vaccinia virus DNA synthesis (IC50 = 10 μM), exhibits notable antimalarial activity against Plasmodium berghei. Additionally, it demonstrates significant antiprion potency, effectively reducing levels of PrPSc [1]-[5]. | |||
T71291 | EICAR | ||
EICAR is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. It is a nucleoside derivative which has both anti-cancer and antiviral effects, and was originally developed for the treatment of leukemia, but was unsuccessful in human clinical trials. It has broad spectrum antiviral effects with activity against vaccinia virus, Semliki forest virus, Junin virus, reovirus, influenza, measles virus and respiratory syncytial virus among others, although it is not active against SARS. T... | |||
T75290 | Enrofloxacin monohydrochloride | ||
Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 为一种针对Mycoplasma bovis具有高效抗菌作用的抗生素,MIC90值为0.312 μg/mL。此外,Enrofloxacin monohydrochloride 亦展现出对牛痘病毒的抗病毒活性。 | |||
T60419 | Cyclic HPMPC | ||
Cyclic HPMPC 是有效的抗病毒剂,可以增加感染致死性牛痘苗病毒 (IHD 株) 小鼠的动脉氧饱和度水平。用 Cyclic HPMPC 治疗可改善先天性豚鼠巨细胞病毒 (GPCMV) 感染的结果并减少豚鼠模型中的病毒复制。 | |||
T35696 |
Olomoucine II
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Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs; IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 μM for Cdk1, -2, -4, -7, and -9, respectively).1It is selective for CDKs over 10 additional kinases (IC50s = >100 μM for all) but does inhibit ERK2 (IC50= 32 μM) and the ATP-binding cassette transporter B1 (ABCB1; IC50= 6.4 μM).1,2Olomoucine II inhibits proliferation of a variety of cancer cells, including those expressing wild-type p53 or mutant p53 (mean IC50s = 7.4 and 10.1 μM, respectively... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T1506 |
Vidarabine
Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A |
Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors |
Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素,能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。 |