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Cat. No.	Product Name	Target	Signaling Pathways
T24941	VMAT2-IN-I HCl VMAT2 IN I Hydrochloride,VMAT2-IN-I Hydrochloride,VMAT2INI Hydrochloride
	VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.
T79061	VMAT2-IN-2 tosylate	Monoamine Transporter	Membrane transporter/Ion channel
	VMAT2-IN-2 tosylate，作为VMAT2的有效抑制剂，应用于迟发性运动障碍的研究。
T7147	Valbenazine NBI-98854	Monoamine Transporter	Membrane transporter/Ion channel
	Valbenazine (NBI-98854) 是一种高度选择性的囊泡单胺转运蛋白 2 (VMAT2) 抑制剂，Ki 为 110-190 nM，用于治疗迟发性运动障碍。
T0719	Tetrabenazine Xenazine,丁苯那嗪,Ro 1-9569	Others; Dopamine Receptor; Monoamine Transporter	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience; Others
	Tetrabenazine (Ro 1-9569) 是 VMAT 抑制剂，用作抗精神病药和治疗各种运动障碍。
T7563	NBI-98782 (+)-α-二氢丁苯那嗪,(+)-α-Dihydrotetrabenazine,(+)-α-DHTBZ,(+)-DTBZ,[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-六氢-9,10-二甲氧基-3-异丁基-2H-苯并[a]喹嗪-2-醇	Monoamine Transporter	Membrane transporter/Ion channel
	NBI-98782 ((+)-α-DHTBZ) 是一种囊泡单胺转运蛋白 (VMAT2) 抑制剂，Ki 为0.97nM。
T13133	Tetrabenazine Metabolite (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ	Monoamine Transporter	Membrane transporter/Ion channel
	Tetrabenazine Metabolite ((-)-β-HTBZ) 是一种囊泡单胺转运蛋白 2 (VMAT2) 抑制剂，是 Tetrabenazine 的一种活性代谢物。Tetrabenazine Metabolite 对 VMAT2 具有高亲和力，其Ki 为13.4 nM。Tetrabenazine Metabolite 常常被用于研究与亨廷顿氏病和其他多动障碍相关的舞蹈病。
T13134	(+)-Tetrabenazine (+)-TBZ,(3R,11bR)-Tetrabenazine,(3R,11bR)-TBZ	Monoamine Transporter	Membrane transporter/Ion channel
	(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) 是一种可逆的囊泡单胺转运蛋白2 (VMAT-2)抑制剂，对 VMAT2转运的抑制作用是VMAT1的10倍。
T41195	FFN 206 dihydrochloride
	FFN 206 dihydrochloride 是一种荧光VMAT2底物，可用于检测细胞培养中的VMAT2亚细胞位置，对DAT 没有显示出可检测的抑制作用。
T41194	FFN 102 mesylate	Others	Others
	FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN)，作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm，在pH 值7.5时为370 nm，在pH 值为5和7.5时，Em-max为435 nm。
T77549	Nurr1 agonist 2	Others	Others
	Nurr1 agonist 2 是一种 Nurr1 激动剂，EC50 值为 0.07 μM。Nurr1 agonist 2 增加 Nurr1 调节基因酪氨酸羟化酶 (TH) 和囊泡氨基酸转运蛋白 2 (VMAT2) 的 mRNA 表达。Nurr1 agonist 2 与重组 Nurr1 配体结合域 (LBD) 结合，Kd 值为 0.14 μM。Nurr1 agonist 2 可用于研究帕金森综合征。
T22452	Valbenazine tosylate 結苯那嗪,NBI-98854	Monoamine Transporter	Membrane transporter/Ion channel
	Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).
T31790	FFN200 dihydrochloride FFN200 HCl,FFN200,FFN 200,FFN-200
	FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.
T70322	Valbenazine dihydrochloride
	Valbenazine dihydrochloride inhibits vesicular monoamine transporter 2 (VMAT2); used to treat tardive dyskinesia.
T31791	FFN246 HCl FFN 246,FFN246 hydrochloride,FFN246,FFN-246
	FFN246 is a fluorescent substrate for both the serotonin transporter and the vesicular monoamine transporter 2 (VMAT2).
T23983	Deutetrabenazine metabolite M4 SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
	Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake
T25750	Lobelane Hydrochloride
	Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.
T78684	FFN246	5-HT Receptor	GPCR/G Protein; Neuroscience
	FFN246作为serotonin transporter (SERT) 和 vesicular monoamine transporter2 (VMAT2) 的荧光双底物探针，具有392/427 nm的激发和发射光谱。该化合物能够通过SERT依赖性积累，标记小鼠脑组织中的5-羟色胺能神经元。
T12190	Trans (2,3)-Dihydrotetrabenazine (2R,3R,11bR)-rel-DHTBZ,(2R,3R,11bR)-rel-Dihydrotetrabenazine	Others	Others
	Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).
T41193	FFN 270
	FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sitesin vivo. Selectively labels NA neurons over other monoamine and CNS targets. Exhibits two resolved absorption/excitation maxima depending on solvent pH (excitation maxima: 320 nm or 365 nm, emission maxima: 475 nm).

化合物

VMAT2-IN-I HCl

Cat.No: T24941

Synonym: VMAT2 IN I Hydrochloride,VMAT2-IN-I Hydrochloride,VMAT2INI Hydrochloride

VMAT2-IN-2 tosylate

Cat.No: T79061

Target: Monoamine Transporter

Cat.No: T7147

Synonym: NBI-98854

Target: Monoamine Transporter

Cat.No: T0719

Synonym: Xenazine,丁苯那嗪,Ro 1-9569

Target: Others, Dopamine Receptor, Monoamine Transporter

Cat.No: T7563

Synonym: (+)-α-二氢丁苯那嗪,(+)-α-Dihydrotetrabenazine,(+)-α-DHTBZ,(+)-DTBZ,[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-六氢-9,10-二甲氧基-3-异丁基-2H-苯并[a]喹嗪-2-醇

Target: Monoamine Transporter

Tetrabenazine Metabolite

Cat.No: T13133

Synonym: (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ

Target: Monoamine Transporter

(+)-Tetrabenazine

Cat.No: T13134

Synonym: (+)-TBZ,(3R,11bR)-Tetrabenazine,(3R,11bR)-TBZ

Target: Monoamine Transporter

FFN 206 dihydrochloride

Cat.No: T41195

FFN 102 mesylate

Cat.No: T41194

Target: Others

Nurr1 agonist 2

Cat.No: T77549

Target: Others

Valbenazine tosylate

Cat.No: T22452

Synonym: 結苯那嗪,NBI-98854

Target: Monoamine Transporter

FFN200 dihydrochloride

Cat.No: T31790

Synonym: FFN200 HCl,FFN200,FFN 200,FFN-200

Valbenazine dihydrochloride

Cat.No: T70322

Cat.No: T31791

Synonym: FFN 246,FFN246 hydrochloride,FFN246,FFN-246

Deutetrabenazine metabolite M4

Cat.No: T23983

Synonym: SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4

Lobelane Hydrochloride

Cat.No: T25750

Cat.No: T78684

Target: 5-HT Receptor

Trans (2,3)-Dihydrotetrabenazine

Cat.No: T12190

Synonym: (2R,3R,11bR)-rel-DHTBZ,(2R,3R,11bR)-rel-Dihydrotetrabenazine

Target: Others

Cat.No: T41193

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