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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20763 |
Betamethasone disodium phosphate
Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616 |
Others | Others |
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) 是一种具有抗炎活性的皮质类固醇,通过减少促炎细胞因子的分泌促进 M1 至 M2 巨噬细胞极化,可用于研究瘢痕疙瘩和类风湿性关节炎。 | |||
T79653 | VISTA-IN-2 | Autophagy | Autophagy |
VISTA-IN-2(Compound 1)是一种抑制V结构域Ig抑制因子(VISTA)的化合物,能够诱导通过自噬(Autophagy)机制的VISTA降解。该化合物在克制VISTA介导的免疫抑制方面有效,提升免疫细胞对抗肿瘤的活性,并在CT26小鼠肿瘤模型中激发抗肿瘤免疫响应,进而抑止肿瘤生长。 | |||
T35362 |
NSC622608
|
Others | Others |
NSC622608 是 V 域 Ig 抑制 T 细胞活化 (VISTA) 的小分子配体,VISTA 是影响 T 细胞攻击肿瘤能力的免疫检查点。 | |||
T76696 |
Onvatilimab
JNJ-61610588 |
Others | Others |
Onvatilimab (JNJ-61610588) 是一种人 IgG1κ 抗 VISTA (T 细胞激活的 V 域 Ig 抑制剂) 单克隆抗体。Onvatilimab 具有抗肿瘤活性,可用于治疗晚期头颈癌。 。 | |||
T77852 |
INX-SM-56
|
||
INX-SM-56是一种用于合成抗VISTA抗体活性分子偶联物的cytotoxin。VISTA代指含V区域免疫球蛋白的T细胞活化抑制因子。 | |||
T81892 |
M351-110
|
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M351-110为T细胞活化V域免疫球蛋白抑制因子(TCR V域)激动剂,应用于癌症研究领域。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00130 |
VISTA Protein, Mouse, Recombinant (hFc)
VISTA,V-set immunoregulatory receptor,Dies1,PD-1H |
Mouse | HEK293 Cells |
VISTA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number is A0A171EBK7. | |||
TMPY-03219 |
VISTA Protein, Human, Recombinant (His)
DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7-H5,PP... |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1. | |||
TMPY-00211 |
VISTA Protein, Mouse, Recombinant (His)
PD-1H,VISTA,V-set immunoregulatory receptor,Dies1 |
Mouse | HEK293 Cells |
VISTA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.2 kDa and the accession number is A0A171EBK7. | |||
TMPY-05184 |
VISTA Protein, Human, Recombinant (His), Biotinylated
DD1alpha,VISTA,B7H5,V-set immunoregulatory receptor... |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1. | |||
TMPY-00501 |
VISTA Protein, Human, Recombinant (hFc)
DD1α,SISP1,C10orf54,DD1alpha,PP2135,V-set immunoregulatory r... |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is AAH20568.1. | |||
TMPY-06894 |
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
GI24,DD1alpha,PP2135,PD-1H,V-set immunoregulatory receptor,<... |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 kDa and the accession number is AAH20568.1. | |||
TMPK-01186 |
B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)
VSIR,B7H5,4632428N05Rik,SISP1,PP2135,Dies1,PD-1H,VISTA |
Human | HEK293 Cells |
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19 kDa and the accession number is Q9H7M9. | |||
TMPK-01185 |
B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)
PP2135,SISP1,VISTA,Gi24,B7H5,4632428N05Rik,Dies1,PD... |
Human | HEK293 Cells |
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q9H7M9. | |||
TMPY-00335 |
VISTA Protein, Rhesus, Recombinant (hFc)
V-set immunoregulatory receptor |
Rhesus | HEK293 Cells |
VISTA Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is F7F6S6. | |||
TMPY-04914 |
VISTA Protein, Cynomolgus, Recombinant (hFc)
C9H10orf54,V-set immunoregulatory receptor |
Cynomolgus | HEK293 Cells |
VISTA Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is F7F6S6. | |||
TMPY-04584 |
VISTA Protein, Cynomolgus, Recombinant (His)
V-set immunoregulatory receptor,C9H10orf54 |
Cynomolgus | HEK293 Cells |
VISTA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is F7F6S6. | |||
TMPY-00258 |
VISTA Protein, Rhesus, Recombinant (His)
V-set immunoregulatory receptor |
Rhesus | HEK293 Cells |
VISTA Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is F7F6S6. | |||
TMPY-00404 |
VISTA Protein, Rat, Recombinant (hFc)
V-set immunoregulatory receptor |
Rat | HEK293 Cells |
VISTA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.7 kDa and the accession number is A0A8J8XY95. |