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Targets Recommended: Others

6

抑制剂 & 化合物

13

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T20763 Betamethasone disodium phosphate

Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616

Others Others
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) 是一种具有抗炎活性的皮质类固醇,通过减少促炎细胞因子的分泌促进 M1 至 M2 巨噬细胞极化,可用于研究瘢痕疙瘩和类风湿性关节炎。
T79653 VISTA-IN-2

Autophagy Autophagy
VISTA-IN-2(Compound 1)是一种抑制V结构域Ig抑制因子(VISTA)的化合物,能够诱导通过自噬(Autophagy)机制的VISTA降解。该化合物在克制VISTA介导的免疫抑制方面有效,提升免疫细胞对抗肿瘤的活性,并在CT26小鼠肿瘤模型中激发抗肿瘤免疫响应,进而抑止肿瘤生长。
T35362 NSC622608

Others Others
NSC622608 是 V 域 Ig 抑制 T 细胞活化 (VISTA) 的小分子配体,VISTA 是影响 T 细胞攻击肿瘤能力的免疫检查点。
T76696 Onvatilimab

JNJ-61610588

Others Others
Onvatilimab (JNJ-61610588) 是一种人 IgG1κ 抗 VISTA (T 细胞激活的 V 域 Ig 抑制剂) 单克隆抗体。Onvatilimab 具有抗肿瘤活性,可用于治疗晚期头颈癌。 。
T77852 INX-SM-56

INX-SM-56是一种用于合成抗VISTA抗体活性分子偶联物的cytotoxin。VISTA代指含V区域免疫球蛋白的T细胞活化抑制因子。
T81892 M351-110

M351-110为T细胞活化V域免疫球蛋白抑制因子(TCR V域)激动剂,应用于癌症研究领域。

化合物

Betamethasone disodium phosphate
Cat.No: T20763
Synonym: Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616
Target: Others
VISTA-IN-2
Cat.No: T79653
Synonym:
Target: Autophagy
NSC622608
Cat.No: T35362
Synonym:
Target: Others
Onvatilimab
Cat.No: T76696
Synonym: JNJ-61610588
Target: Others
INX-SM-56
Cat.No: T77852
Synonym:
Target:
M351-110
Cat.No: T81892
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00130 VISTA Protein, Mouse, Recombinant (hFc)

VISTA,V-set immunoregulatory receptor,Dies1,PD-1H

Mouse HEK293 Cells
VISTA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number is A0A171EBK7.
TMPY-03219 VISTA Protein, Human, Recombinant (His)

DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7-H5,PP...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
TMPY-00211 VISTA Protein, Mouse, Recombinant (His)

PD-1H,VISTA,V-set immunoregulatory receptor,Dies1

Mouse HEK293 Cells
VISTA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.2 kDa and the accession number is A0A171EBK7.
TMPY-05184 VISTA Protein, Human, Recombinant (His), Biotinylated

DD1alpha,VISTA,B7H5,V-set immunoregulatory receptor...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
TMPY-00501 VISTA Protein, Human, Recombinant (hFc)

DD1α,SISP1,C10orf54,DD1alpha,PP2135,V-set immunoregulatory r...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is AAH20568.1.
TMPY-06894 VISTA Protein, Human, Recombinant (His & Avi), Biotinylated

GI24,DD1alpha,PP2135,PD-1H,V-set immunoregulatory receptor,<...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 kDa and the accession number is AAH20568.1.
TMPK-01186 B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)

VSIR,B7H5,4632428N05Rik,SISP1,PP2135,Dies1,PD-1H,VISTA

Human HEK293 Cells
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19 kDa and the accession number is Q9H7M9.
TMPK-01185 B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)

PP2135,SISP1,VISTA,Gi24,B7H5,4632428N05Rik,Dies1,PD...

Human HEK293 Cells
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q9H7M9.
TMPY-00335 VISTA Protein, Rhesus, Recombinant (hFc)

V-set immunoregulatory receptor

Rhesus HEK293 Cells
VISTA Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is F7F6S6.
TMPY-04914 VISTA Protein, Cynomolgus, Recombinant (hFc)

C9H10orf54,V-set immunoregulatory receptor

Cynomolgus HEK293 Cells
VISTA Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is F7F6S6.
TMPY-04584 VISTA Protein, Cynomolgus, Recombinant (His)

V-set immunoregulatory receptor,C9H10orf54

Cynomolgus HEK293 Cells
VISTA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is F7F6S6.
TMPY-00258 VISTA Protein, Rhesus, Recombinant (His)

V-set immunoregulatory receptor

Rhesus HEK293 Cells
VISTA Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is F7F6S6.
TMPY-00404 VISTA Protein, Rat, Recombinant (hFc)

V-set immunoregulatory receptor

Rat HEK293 Cells
VISTA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.7 kDa and the accession number is A0A8J8XY95.

重组蛋白

VISTA Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00130
Species: Mouse
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His)
Cat.No: TMPY-03219
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00211
Species: Mouse
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05184
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00501
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06894
Species: Human
Expression System: HEK293 Cells
B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)
Cat.No: TMPK-01186
Species: Human
Expression System: HEK293 Cells
B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01185
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-00335
Species: Rhesus
Expression System: HEK293 Cells
VISTA Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-04914
Species: Cynomolgus
Expression System: HEK293 Cells
VISTA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04584
Species: Cynomolgus
Expression System: HEK293 Cells
VISTA Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-00258
Species: Rhesus
Expression System: HEK293 Cells
VISTA Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-00404
Species: Rat
Expression System: HEK293 Cells
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