Cat. No. | Product Name | Target | Signaling Pathways |
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TP2165 |
Urotensin II, mouse acetate (9047-55-6 free base)
Urotensin II, mouse acetate |
GPR | Endocrinology/Hormones; GPCR/G Protein |
Urotensin II, mouse acetate (9047-55-6 free base) 是孤儿 GPR14 或 SENR 的内源性配体。它是一种强效血管收缩剂。 | |||
TP1816 |
Urotensin II, mouse
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Jump to search UTS2 Identifiers Aliases UTS2, PRO1068, U-II, UCN2, UII, urotensin 2 External IDs OMIM: 604097 MGI: 1346329 HomoloGene: 4939 GeneCards: UTS2 hide Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.23 Start 7,843,083 bp[1] En | |||
TP2166 |
Urotensin II, mouse TFA (9047-55-6 free base)
Urotensin II, mouse TFA |
GPR | Endocrinology/Hormones; GPCR/G Protein |
Urotensin II, mouse TFA is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor. | |||
T75962 |
Urotensin II, mouse acetate
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Urotensin II, mouse acetate,是孤儿G蛋白偶联受体(GPR14或SENR)的一种内源性配体,具有显著的血管收缩活性并在中枢神经系统中发挥重要功能。 | |||
T75961 |
Urotensin II, mouse TFA
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Urotensin II, mouse TFA 为孤儿G蛋白偶联受体GPR14或SENR的内源性配体,具有强效血管收缩作用,并在中枢神经系统中发挥重要角色。 | |||
T12848 |
SB-657510
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Others; Neurotensin Receptor | GPCR/G Protein; Others |
SB-657510 是 urotensin II (UII) receptor (UT) 拮抗剂。 对于人,猴,猫,大鼠和小鼠的UT 的 Ki 值分别为 61、17、30、65 和 56 nM。SB-657510 通过抑制 UII 诱导的人类血管内皮细胞中炎性介质,如粘附分子,使细胞因子和组织因子上调从而发挥抗炎作用。SB 657510对糖尿病小鼠模型中糖尿病相关动脉粥样硬化疾病具有治疗作用。 | |||
T36373 |
Urocortin II (mouse) (trifluoroacetate salt)
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Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II shares 34 and 42% sequence homology with rat CRF and urocortin . It is expressed in mouse paraventricular, supraoptic, and arcuate nuclei of the hypothalamus, the locus coeruleus, and in motor nuclei of the brainstem and spinal ventral horn. Urocortin II selectively binds to CRF... | |||
T35814 |
Urocortin III (human) (trifluoroacetate salt)
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Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively).... |