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Search Results for " uridine triphosphate "

11

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T36299	Uridine triphosphate 13C9,15N2 sodium Uridine triphosphate 13C9,15N2 sodium
	Uridine triphosphate 13C9,15N2 (UTP 13C9,15N2) sodium, a labeled form of uridine triphosphate sodium, facilitates nucleic acid synthesis.
T83778	5-(3-Aminoallyl)uridine-5'-O-triphosphate sodium AA-UTP,aminoallyl-UTP
	aminoallyl-UTP（5-(3-氨基丙烯)尿苷-5'-O-三磷酸）是一种经过胺修饰的核苷酸，用于合成亲和标记的UTP。aminoallyl-UTP被用于合成互补RNA（cRNA）和细菌转移信使RNA（tmRNA）中，进而用于生成用于微阵列的荧光标记探针。
T36866	3-Deazauridine 4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮,NSC 126849	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	3-Deazauridine (NSC-126849) 是一种尿苷的结构类似物，通过竞争性抑制胞苷三磷酸合成酶来抑制胞苷-5'-三磷酸的生物合成，这种合成酶被认为是这种核苷类似物的主要作用方式。
T1408	Capecitabine Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Capecitabine (Capecitibine) 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T1600	Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Doxifluridine (AMC 0101) 是一种胸苷磷酸化酶活化剂，对 PC9-DPE2细胞的 IC50为0.62 μM。它是具有抗肿瘤活性的抗肿瘤剂 5-fluorouracil (5-FU) 的氟嘧啶衍生物和口服前药。
T83270	6-Azauridine triphosphate 6-Azauridine 5′-triphosphate
	6-Azauridine triphosphate（6-Azauridine 5′-triphosphate）为尿苷三磷酸（UTP）核苷酸类似物，应用于 RNA 合成和转录调控机制研究。
T40753	Cytidine-5'-triphosphate Cytidine triphosphate,Cytidine-5'-triphosphate,5'-CTP
	Cytidine 5'-triphosphate (5'-CTP), also known as cytidine triphosphate, is a nucleoside triphosphate that plays a crucial role as a building block for nucleotides and nucleic acids, as well as lipid biosynthesis. It is synthesized through the catalytic action of cytidine triphosphate synthase, which converts uridine 5'-triphosphate (UTP) to cytidine 5'-triphosphate. Cytidine 5'-triphosphate is an essential biomolecule in T. gondii's de novo pyrimidine biosynthetic pathway.
T74176	Pseudouridine 5'-triphosphate trisodium
	Pseudouridine 5'-triphosphate (Pseudo-UTP) 是聚合酶介导的 RNA 合成中常用的修饰核苷酸之一。与含有 UTP 的未修饰的 mRNA 相比，含Pseudo-UTP 的 mRNA 的显示出更好的核酸酶稳定性，免疫原性和翻译特性。
T70859	ent-Abacavir
	ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuroni...
T68631	Carbetimer
	Carbetimer is a partially imidized copolymer of ethylene & maleic anhydride with average MW approx 1,200 daltons; capable of specific stimulation of immune response. Carbetimer is a low molecular weight polymer derived from ethylene and maleic anhydride with potent antineoplastic activity. Preclinical studies have shown antitumor effects against many tumor cell lines including B 16 melanoma. Its antitumor actions are felt to include both reduction of uridine and cytidine nucleoside triphosphate ...
T36894	5-Bromouridine
	5-Bromouridine is a brominated analog of the nucleoside uridine .1It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine .25-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions....

化合物

Uridine triphosphate 13C9,15N2 sodium

Cat.No: T36299

Synonym: Uridine triphosphate 13C9,15N2 sodium

5-(3-Aminoallyl)uridine-5'-O-triphosphate sodium

Cat.No: T83778

Synonym: AA-UTP,aminoallyl-UTP

Cat.No: T36866

Synonym: 4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮,NSC 126849

Target: Nucleoside Antimetabolite/Analog

Cat.No: T1408

Synonym: Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T1600

Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

6-Azauridine triphosphate

Cat.No: T83270

Synonym: 6-Azauridine 5′-triphosphate

Cytidine-5'-triphosphate

Cat.No: T40753

Synonym: Cytidine triphosphate,Cytidine-5'-triphosphate,5'-CTP

Pseudouridine 5'-triphosphate trisodium

Cat.No: T74176

Cat.No: T70859

Cat.No: T68631

Cat.No: T36894

Cat. No.	Product Name	Target	Signaling Pathways
T7711	Uridine triphosphate 尿苷5'-三磷酸酯,UTP,Uridine 5'-triphosphate,三磷酸尿苷	Others; Endogenous Metabolite	Metabolism; Others
	Uridine triphosphate (Uridine 5'-triphosphate) 是一种核苷酸，调节胰腺内分泌和外分泌、增殖、通道、转运体和细胞内信号传导的功能。
T8393	Uridine triphosphate trisodium salt UTP, Trisodium Salt,Uridine 5'-triphosphate trisodium salt,尿苷-5'-三磷酸三钠盐,Uridine triphosphate (trisodium salt)	Others	Others
	Uridine triphosphate trisodium salt (UTP, Trisodium Salt) 是一种核苷酸，在正常和疾病状态，均能够调节胰腺内分泌和外分泌、通道、增殖、转运体和细胞内信号传导的功能。
T4922	Uridine 5′-triphosphate tris salt 尿苷-5′-三磷酸酯三羟甲基氨基甲烷盐,Uridine 5'-triphosphoric acid	Others; Endogenous Metabolite	Metabolism; Others
	Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) 是 P2Y 受体的激动剂，已用于研究细胞内 Ca2+ 的浓度，以及用于体外激酶测定的磷酸盐供体。
T73926	Uridine 5'-triphosphate tris salt
	Uridine 5'-triphosphate tris salt 是一种内源性代谢产物。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。

天然产物

Uridine triphosphate

Cat.No: T7711

Synonym: 尿苷5'-三磷酸酯,UTP,Uridine 5'-triphosphate,三磷酸尿苷

Target: Others, Endogenous Metabolite

Uridine triphosphate trisodium salt

Cat.No: T8393

Synonym: UTP, Trisodium Salt,Uridine 5'-triphosphate trisodium salt,尿苷-5'-三磷酸三钠盐,Uridine triphosphate (trisodium salt)

Target: Others

Uridine 5′-triphosphate tris salt

Cat.No: T4922

Synonym: 尿苷-5′-三磷酸酯三羟甲基氨基甲烷盐,Uridine 5'-triphosphoric acid

Target: Others, Endogenous Metabolite

Uridine 5'-triphosphate tris salt

Cat.No: T73926

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

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