首页工具

搜索结果

Search Results for " tyrosine kinase-in-7 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T77746	Tyrosine kinase-IN-7	EGFR; Antiviral	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tyrosine kinase-IN-7 是一种有效的酪氨酸激酶 EGFR 抑制剂，抑制 EGFR(WT) 和 EGFR(T790M) ，在多种癌细胞系中显示出抗癌和抗肿瘤活性。Tyrosine kinase-IN-7 具有潜在的抗炎和抗病毒活性。
T9973	FAK-IN-7	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	FAK-IN-7 有潜在的抗增殖活性，是一种 FAK 抑制剂。
T11299	FLT3-IN-4 FLT3 inhibitor 9u	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	FLT3-IN-4 (FLT3 inhibitor 9u) 是一种口服有效的 Fms 样酪氨酸受体激酶 3 (FLT3; IC50= 7 nM) 抑制剂，可用于急性髓性白血病的研究。
T78943	Syk-IN-7	Syk	Angiogenesis; Tyrosine Kinase/Adaptors
	Syk-IN-7（化合物17）是一类特定的酪氨酸激酶（SYK）抑制剂。
T70377	BAY 61-3606 HCl
	BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i...
T71082	DW532
	DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 values were 4.9 and 5.5 μmol/L, respectively), and suppressed their downstream signaling. DW532 dose-dependently inhibited tubulin polymerization via direct binding to tubulin, thus disrupting the mitotic spindle assembly and leading to abnormal cell division. In a panel of human ca...