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Search Results for " thromboplastin "

6

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T35579	PKSI-527
	PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times. In vivo, PKSI-527 (300 mg/kg per day) reduces hyperplasia, pannus formation, and infiltration of in...
T26702	AZ12971554 AZ 12971554,AZ-12971554
	AZ12971554 is a potent inhibitor of human thrombin. Ki = 0.3nM, Activated partial thromboplastin time (APTT) IC50 = 0.68µM, Ecarin clotting time (ECT) IC50 = 0.16µM in human plasma.
T14682	BMS-962212	Others	Others
	BMS-962212, a direct, reversible, and selective factor XIa (FXIa) inhibitor, demonstrates fast pharmacodynamic (PD) response onset and rapid elimination with a well-tolerated profile. It dependently increases activated partial thromboplastin time and decreases FXI clotting activity exposure [1].
T35939	Dabigatran Acyl-β-D-Glucuronide
	Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.
T27698	JTV-803 mesylate JTV803,JTV 803,JTV-803
	JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its
T83873	Dabigatran Acyl-β-D-Glucuronide TFA Dabigatran β-1-O-Acyl Glucuronide
	Dabigatran acyl-β-D-glucuronide是凝血酶抑制剂dabigatran的一种活性代谢产物，主要通过UDP-葡萄糖醛酸转移酶(UGT)的UGT2B15亚型形成。在人体去除血小板的贫血浆中，Dabigatran acyl-β-D-glucuronide (0.46 µM) 能增加活化部分凝血活酶时间(aPTT)。

化合物

Cat.No: T35579

Cat.No: T26702

Synonym: AZ 12971554,AZ-12971554

Cat.No: T14682

Target: Others

Dabigatran Acyl-β-D-Glucuronide

Cat.No: T35939

JTV-803 mesylate

Cat.No: T27698

Synonym: JTV803,JTV 803,JTV-803

Dabigatran Acyl-β-D-Glucuronide TFA

Cat.No: T83873

Synonym: Dabigatran β-1-O-Acyl Glucuronide

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05094	Tissue Factor Protein, Cynomolgus, Recombinant (His) coagulation factor III (thromboplastin, tissue fact...	Cynomolgus	HEK293 Cells
	Tissue Factor Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is XP_005542723.1.
TMPY-02530	Tissue Factor Protein, Human, Recombinant (His) CD142,coagulation factor III (thromboplastin, tissu...	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P13726.
TMPY-02318	Tissue Factor Protein, Rabbit, Recombinant (His) coagulation factor III (thromboplastin, tissue fact...	Rabbit	HEK293 Cells
	Tissue Factor Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P24055.
TMPY-03209	Tissue Factor Protein, Rat, Recombinant (His) coagulation factor III (thromboplastin, tissue fact...	Rat	HEK293 Cells
	Tissue Factor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is Q66HI4.
TMPY-02537	Tissue Factor Protein, Human, Recombinant (hFc) coagulation factor III,coagulation factor III (thrombopl...	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P13726.
TMPY-01325	Tissue Factor Protein, Mouse, Recombinant (His) Cf-3,AA409063,CD142,coagulation factor III (thromboplast...	Mouse	HEK293 Cells
	Tissue Factor Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A0R4J088.
TMPK-00993	Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation...	Canine	HEK293 Cells
	Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPY-05083	Tissue Factor Protein, Human, Recombinant (aa 1-295, His) coagulation factor 3,TF,TFA,coagulation factor III,coagulati...	Human	Baculovirus Insect Cells
	Tissue Factor Protein, Human, Recombinant (aa 1-295, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P13726-1.
TMPY-06957	Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated TFA,coagulation factor 3,coagulation factor III,CD142,coagul...	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.34 kDa and the accession number is P13726.
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His) coagulation factor 11,coagulation factor XI,FXI	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...
TMPH-00938	ANXA5 Protein, Human, Recombinant (His) ANXA5,Annexin A5,Annexin V,Calphobindin I (CPB-I),ENX2,Endon...	Human	P. pastoris (Yeast)
	This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. ANXA5 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P08758.
TMPJ-00844	ANXA8 Protein, Human, Recombinant Vascular Anticoagulant-β,Annexin-8,Annexin A8,VAC-Beta,ANX8,...	Human	E. coli
	Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect i...

重组蛋白

Tissue Factor Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05094

Species: Cynomolgus

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-02530

Species: Human

Expression System: HEK293 Cells

Tissue Factor Protein, Rabbit, Recombinant (His)

Cat.No: TMPY-02318

Species: Rabbit

Expression System: HEK293 Cells

Tissue Factor Protein, Rat, Recombinant (His)

Cat.No: TMPY-03209

Species: Rat

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02537

Species: Human

Expression System: HEK293 Cells

Tissue Factor Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01325

Species: Mouse

Expression System: HEK293 Cells

Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Cat.No: TMPK-00993

Species: Canine

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (aa 1-295, His)

Cat.No: TMPY-05083

Species: Human

Expression System: Baculovirus Insect Cells

Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06957

Species: Human

Expression System: HEK293 Cells

Coagulation factor XI/F11 Protein, Human, Recombinant (His)

Cat.No: TMPY-01104

Species: Human

Expression System: HEK293 Cells

ANXA5 Protein, Human, Recombinant (His)

Cat.No: TMPH-00938

Species: Human

Expression System: P. pastoris (Yeast)

ANXA8 Protein, Human, Recombinant

Cat.No: TMPJ-00844

Species: Human

Expression System: E. coli

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