Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22003 |
2,3-dihydrothieno-Thiadiazole Carboxylate
|
P450 | Metabolism |
2,3-dihydrothieno-Thiadiazole Carboxylate 是一种 CYP450(CYP2E1 和 CYP2B4)抑制剂。 | |||
T19784 |
DBT
NSC701994,4,7-Bis(thiophen-2-yl)benzo[c][1,2,5]thiadiazole,NSC 701994,NSC-701994 |
Others | Others |
DBT (NSC-701994) 是一种远红/近红外荧光探针,用于肿瘤相关蛋白的特异性体外和体内成像。 | |||
T66904 |
2,5-Dimercapto-1,3,4-thiadiazole
|
||
2,5-Dimercapto-1,3,4-thiadiazole 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66904,CAS号为 1072-71-5。 | |||
T66917 |
5-Methyl-1,3,4-thiadiazole-2-thiol
|
||
5-Methyl-1,3,4-thiadiazole-2-thiol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66917,CAS号为 29490-19-5。 | |||
T66861 |
3-Chloro-4-morpholino-1,2,5-thiadiazole
|
||
3-Chloro-4-morpholino-1,2,5-thiadiazole 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66861,CAS号为 30165-96-9。 | |||
T13018 |
SU3327
halicin |
JNK | MAPK |
SU3327 (halicin) 是具有底物竞争性的 JNK 选择性抑制剂,IC50为 0.7 μM。它还抑制 JNK 和 JIP 之间的蛋白相互作用,IC50值为 239 nM。 | |||
T10716 |
CCR7 Ligand 1
CCR7-Cmp2105 |
Others | Others |
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM | |||
T37222 |
GLS1 Inhibitor
|
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GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM).1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro(GI50= 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. 1.Finlay, M.R.V., Anderton, M., Bailey, A., et al.Discovery of a thiadiazole-pyridazine-based allosteric glutaminase 1 inhibitor series that demons... | |||
T37832 |
CAY10761
CAY10761 |
||
CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) and urease from jack bean, P. mirabilis, and B. pasteurii (IC50s = 0.093, <0.125, and 0.089 mM, respectively, at pH 8.2).3,4 |1. Khan, K.M., Fatima, N., Rasheed, M., et al. 1,3,4-Oxadiazole-2(3H)-thione and its analogues: A new class of non-competitive nucleotide pyrophosphatases/p... |