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Search Results for " tetrahydrobiopterin "

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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T7461 2,4-Diamino-6-hydroxypyrimidine

DAHP,2,4-二氨基-6-羟基嘧啶

Reactive Oxygen Species; NO Synthase Immunology/Inflammation; Metabolism; NF-κB
2,4-Diamino-6-hydroxypyrimidine (DAHP) 是GTP cyclohydrolase I(蛋白从头合成中的限速酶) 的选择性抑制剂。它能够抑制NO 的产生以及阻断 Tetrahydrobiopterin (BH4) 的合成。

化合物

2,4-Diamino-6-hydroxypyrimidine
Cat.No: T7461
Synonym: DAHP,2,4-二氨基-6-羟基嘧啶
Target: Reactive Oxygen Species, NO Synthase
Cat. No. Product Name Target Signaling Pathways
T17056 Tetrahydrobiopterin

Sapropterin,BH4,(Rac)-Sapropterin

NOS; Endogenous Metabolite Immunology/Inflammation; Metabolism
Tetrahydrobiopterin (BH4) 是芳香族氨基酸羟化酶的辅因子, 也是一氧化氮合酶 (NOS) 的必需辅因子,可用于研究如高血压、高胆固醇血症、糖尿病等内皮功能障碍。
T19160 7,8-Dihydro-L-biopterin

Endogenous Metabolite Metabolism
7,8-Dihydro-L-biopterin 是一种四氢生物蝶呤的氧化产物。
T38250 L-Sepiapterin

L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-de...

天然产物

Tetrahydrobiopterin
Cat.No: T17056
Synonym: Sapropterin,BH4,(Rac)-Sapropterin
Target: NOS, Endogenous Metabolite
7,8-Dihydro-L-biopterin
Cat.No: T19160
Synonym:
Target: Endogenous Metabolite
L-Sepiapterin
Cat.No: T38250
Synonym:
Target:
TargetMol Loading
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