Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7111 |
Tenofovir Disoproxil
替诺福韦酯,GS 4331,Bis(POC)-PMPA |
HBV; HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Tenofovir Disoproxil (GS 4331) 是一种核苷酸逆转录酶抑制剂,用于治疗 HIV 和慢性乙型肝炎。 | |||
T2409L |
Tenofovir Disoproxil Fumarate
GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯 |
HBV; HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) 是一种核苷酸逆转录酶抑制剂,有潜力研究艾滋病和慢性乙型肝炎。 | |||
T28945 |
Tenofovir disoproxil aspartate
CKD-390,CKD390,CKD 390 |
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Tenofovir disoproxil aspartate, a nucleotide reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection. | |||
T12127 |
9-Propenyladenine
Mutagenic Impurity of Tenofovir Disoproxil,替诺福韦酯杂质,Tenofovir Impurity 2 |
Others | Others |
9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. | |||
T13457 |
(Z)-9-Propenyladenine
(Z)-替诺福韦酯杂质,(Z)-Mutagenic Impurity of Tenofovir Disoproxil |
Others | Others |
(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. | |||
T21775 | Tenofovir maleate | ||
Tenofovir maleate (GS 1278 maleate) 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂,用于治疗HIV 和慢性乙型肝炎。 | |||
T37523 |
Tenofovir diphosphate (sodium salt)
|
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Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenof... |