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12

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2141	Mecamylamine hydrochloride 盐酸美加明,Inversine,Mevasin	AChR	Neuroscience
	Mecamylamine hydrochloride (Mevasin) 是一种易穿过血脑屏障的烟碱拮抗剂，用作高血压的神经节阻滞剂，具有抗神经疾病作用。
T26357	Pitstop 2	Apoptosis	Apoptosis
	Pitstop2 是一种选择性的两性蛋白结合的网格蛋白末端结构域抑制剂，IC50 值为 12 μM。 Pitstop2 严重干扰受体介导的内吞作用、HIV 进入和突触小泡循环。
TP2222	APTSTAT3-9R	Others	Others
	APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though
TP2222L	APTSTAT3-9R acetate	STAT	JAK/STAT signaling; Stem Cells
	APTSTAT3-9R acetate 是一种特异性肽结合 STAT3，具有抗增殖和抗肿瘤活性。 APTSTAT3-9R acetate 并通过特异性阻断 STAT3 磷酸化来抑制 STAT3 活化和下游信号传导。
T126527	Poststerone
	Poststerone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126527。
T25256	Pitstop1 Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1
	Clathrin-IN-1 is a selective clathrin inhibitor that acts by addressing clathrin function in cell physiology with potential applications as an inhibitor of virus and pathogen entry and as a modulator of cell signaling.
TP2421	Ysdspstst peptide
	Ysdspstst peptide is a biochemical.
T25973	Poststatin
	Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3.
T34055	Phtstllap
	Phtstllap is a luteinizing hormone-releasing factor
T61625	GABAA receptor agonist 2
	GABAA receptor agonist 2 (compound 4c) is a highly potent GABAA receptor agonist which exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, GABAA receptor agonist 2 produces GABAergic effects. Notably, Compound 4c holds promise for depression research [1].
T60842	GABAA receptor agonist 1
	GABAA receptor agonist 1 (compound 3e) 是有效的 GABAA 受体激动剂，它结合在GABAA 受体的 GABAA 结合位点结合以产生 GABA 能效应。GABAA receptor agonist 1 在 FST 和 TST 抑郁症的经典小鼠模型中具有抗抑郁活性，在抑郁症研究中具有潜力。
T65440	Sodium Thiosulfate Pentahydrate
	Sodium thiosulfate (Pentahydrate) is an antioxidant and antifungal. Sodium thiosulfate protects against cisplatin-induced hearing loss in children and is not associated with serious adverse events attributed to its use[3]. The addition of sodium thiosulfate, administered 6 hours after cisplatin chemotherapy, resulted in a lower incidence of cisplatin-induced hearing loss among children with standard-risk hepatoblastoma, without jeopardizing overall or event-free survival[4]. Calciphylaxis is a p...

化合物

Mecamylamine hydrochloride

Cat.No: T2141

Synonym: 盐酸美加明,Inversine,Mevasin

Target: AChR

Cat.No: T26357

Target: Apoptosis

Cat.No: TP2222

Target: Others

APTSTAT3-9R acetate

Cat.No: TP2222L

Target: STAT

Cat.No: T126527

Cat.No: T25256

Synonym: Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1

Ysdspstst peptide

Cat.No: TP2421

Cat.No: T25973

Cat.No: T34055

GABAA receptor agonist 2

Cat.No: T61625

GABAA receptor agonist 1

Cat.No: T60842

Sodium Thiosulfate Pentahydrate

Cat.No: T65440

Cat. No.	Product Name	Target	Signaling Pathways
T11218	ε-Viniferin epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体	P450	Metabolism
	ε-Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera，是 Resveratrol 的二聚体，能够抑制 CYP 家族,其 Ki=0.5~20 μM，具有抗氧化作用。

天然产物

Cat.No: T11218

Synonym: epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体

Target: P450

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