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Search Results for " tslp "
Targets Recommended: Others

3

抑制剂 & 化合物

19

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T77359 Tezepelumab

Tezepelumab-ekko,MEDI 19929,AMG 157

 Others Others
Tezepelumab (AMG 157) 是一种人源化靶向 TSLP 的单克隆抗体 (IgG2λ)，阻止TSLP 与其异二聚体受体相互作用。Tezepelumab 可用于研究晚期哮喘疾病。
T9901A-011 Lunsekimig

SAR443765
Lunsekimig (SAR443765) 是一种 IL-13/TSLP 双抗，将靶向 IL-13 和靶向 TSLP 的重链可变区 (VHH) 连接在一起的纳米抗体，可用于哮喘研究。
T82507 Ecleralimab

CSJ-117,NVP-CSJ117
Ecleralimab (CSJ-117; NVP-CSJ117) 是一种 Fab-IgG1-λ2 类型的单克隆抗体，专一性靶向胸腺基质淋巴生成素（TSLP）。该抗体主要采用 CHO（Chinese Hamster Ovary）细胞表达系统生产。

化合物

Tezepelumab
Cat.No: T77359
Synonym: Tezepelumab-ekko,MEDI 19929,AMG 157
Target: Others
Lunsekimig
Cat.No: T9901A-011
Synonym: SAR443765
Target:
Ecleralimab
Cat.No: T82507
Synonym: CSJ-117,NVP-CSJ117
Target:
Species：
Human (12)
Mouse (4)
Cynomolgus (3)
Expression System：
HEK293 Cells (18)
E. coli (1)
Tag：
C-His (7)
C-His-Avi (5)
C-hFc (4)
C-6xHis (1)
His (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

 Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPY-02428 TSLP Protein, Mouse, Recombinant (His)

thymic stromal lymphopoietin,TSLP

 Mouse HEK293 Cells
TSLP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9JIE6.
TMPK-00037 TSLP Protein, Human, Recombinant (His & Avi)

TSLP,thymic stromal lymphopoietin

 Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi...
TMPK-00039 TSLP Protein, Human, Recombinant (His & Avi), Biotinylated

TSLP,thymic stromal lymphopoietin

 Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells ...
TMPJ-01338 TSLP Protein, Mouse, Recombinant (hFc)

Thymic stromal lymphopoietin,Thymic stroma-derived lymphopoi...

 Mouse HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells ...
TMPK-00482 TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

thymic stromal lymphopoietin,TSLP

 Cynomolgus HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in...
TMPK-00040 TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated

Thymic stromal lymphopoietin,TSLP

 Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated is expressed in HEK293 m...
TMPK-00038 TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

thymic stromal lymphopoietin,TSLP

 Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) is expressed in HEK293 mammalian cells...
TMPY-05453 TSLP Protein, Cynomolgus, Recombinant (His)

thymic stromal lymphopoietin

 Cynomolgus HEK293 Cells
TSLP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.5 kDa and the accession number is A0A7N9CAT7.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

 Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06505 TSLP Protein, Human, Recombinant (hFc)

thymic stromal lymphopoietin

 Human HEK293 Cells
TSLP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.50 kDa and the accession number is NP_149024.1.
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His)

CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,

Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TMPY-05756 TSLP Protein, Human, Recombinant (His), Biotinylated

thymic stromal lymphopoietin

 Human HEK293 Cells
TSLP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPJ-00530 TSLPR Protein, Mouse, Recombinant (hFc)

CRLF2,CRL2 cytokine receptor,TSLPR,CRL2,P2RY8/CRLF2...

 Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
TMPJ-00531 TSLPR Protein, Mouse, Recombinant (His)

Cytokine receptor-like 2,Thymic stromal-derived lymphopoieti...

 Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1.
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His)

CRL2,CRLF2Y,TSLPR,cytokine receptor-like factor 2

 Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is D0E2W4.
TMPY-06604 IL-7RA & TSLPR Heterodimer Protein, Human, Recombinant (His)

Human HEK293 Cells
IL-7RA & TSLPR Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.34 kDa and the accession number is P16871-1.
TMPY-05769 CRLF2/TSLPR Protein, Human, Recombinant (hFc)

CRLF2Y,cytokine receptor-like factor 2,CRL2,TSLPR

 Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.91 kDa and the accession number is D0E2W4.
TMPK-01202 CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated

C1QR1,C1q/MBL/SPA receptor,ECSM3,C1qRp,C1qR(p),C1qR,dJ737E23...

 Human HEK293 Cells
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.

重组蛋白

TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
TSLP Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02428
Species: Mouse
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00037
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00039
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01338
Species: Mouse
Expression System: HEK293 Cells
TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPK-00482
Species: Cynomolgus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated
Cat.No: TMPK-00040
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)
Cat.No: TMPK-00038
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05453
Species: Cynomolgus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06505
Species: Human
Expression System: HEK293 Cells
TSLPR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05756
Species: Human
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00530
Species: Mouse
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00531
Species: Mouse
Expression System: HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (His)
Cat.No: TMPY-05242
Species: Human
Expression System: HEK293 Cells
IL-7RA & TSLPR Heterodimer Protein, Human, Recombinant (His)
Cat.No: TMPY-06604
Species: Human
Expression System: HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05769
Species: Human
Expression System: HEK293 Cells
CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
Cat.No: TMPK-01202
Species: Human
Expression System: HEK293 Cells
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