Cat. No. | Product Name | Target | Signaling Pathways |
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T68257 |
Hydromethylthionine HBr
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Hydromethylthionine, also known as LMTM and Leucomethylene Blue, is a apotent tau aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Hydromethylthionine showed pharmacological activity on brain structure and function as both monotherapy and as an add-on to symptomatic treatment in certain patients with Alzheimer’s disease. | |||
T7003 |
Leucomethylene blue mesylate
N3,N3,N7,N7-四甲基-10H-吩噻嗪-3,7-二胺二甲磺酸盐,TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate |
Beta Amyloid; Microtubule Associated | Cytoskeletal Signaling; Neuroscience |
Leucomethylene blue mesylate (TRx0237 mesylate) 是一种 Methylene blue (亚甲基蓝)的还原形式, 亚甲基蓝是一种化学指示剂和生物染色剂。它是一种具有口服活性的二代 tau 蛋白聚集的抑制剂 (Ki=为0.12 μM),可用于阿尔兹海默症的研究。 |