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抑制剂 & 化合物

13

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Cat. No. Product Name Target Signaling Pathways
T80559 Duvakitug

Duvakitug为针对TNFSF15/TL1A的人源IgG1-λ2型单克隆抗体,在CHOK1SV细胞系的内源性谷氨酰胺合成酶(GS)阳性细胞中表达,适用于克罗恩病(Crohn's Disease, CD)研究。
T80560 Tulisokibart

PRA-023,PRA023

Tulisokibart (PRA023)为人源化小鼠IgG1-κ型单克隆抗体,专一性靶向TNFSF15/TL1A。应用于炎症及纤维化疾病如克罗恩病(Crohn's Disease, CD)的研究。

化合物

Duvakitug
Cat.No: T80559
Synonym:
Target:
Tulisokibart
Cat.No: T80560
Synonym: PRA-023,PRA023
Target:
Cat. No. Product Name Species Expression System
TMPY-04645 TL1A/TNFSF15 Protein, Human, Recombinant (hFc)

TL1,tumor necrosis factor (ligand) superfamily, mem...

Human HEK293 Cells
TL1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is A0A0U5JA19.
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant

TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...

Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPK-01012 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TL1,TNFSF15,VEGI,VEGI-251,TL1A,VE...

Mouse HEK293 Cells
TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8.
TMPK-01013 TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)

VEGI192A,TL1,VEGI-251,TL1A,TNFSF1...

Mouse HEK293 Cells
TNFSF15 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 48.8 kDa and the accession number is Q5UBV8.
TMPK-01011 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)

TNFSF15,VEGI-251,TL1A,VEGI,TL1,VE...

Mouse HEK293 Cells
TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8.
TMPY-04978 TL1A/TNFSF15 Protein, Human, Recombinant (rFc)

VEGI,VEGI192A,TL1,TL1A,tumor necr...

Human HEK293 Cells
TL1A Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 48 kDa and the accession number is A0A0U5JA19.
TMPY-05802 TL1A/TNFSF15 Protein, Human, Recombinant (His)

TL1A,VEGI,VEGI192A,tumor necrosis factor (...

Human HEK293 Cells
TL1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is A0A0U5JA19.
TMPK-00143 TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)

TL1A,TL1,TNFSF15,VEGI,VEGI192A,VE...

Human HEK293 Cells
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight...
TMPY-04979 TL1A/TNFSF15 Protein, Human, Recombinant (mFc)

VEGI,tumor necrosis factor (ligand) superfamily, member 15,<...

Human HEK293 Cells
TL1A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.1 kDa and the accession number is A0A0U5JA19.
TMPK-00489 TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TNFSF15,TNF superfamily member 15,TL1,VEGI192A,...

Cynomolgus,Rhesus HEK293 Cells
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weigh...
TMPY-03067 TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)

tumor necrosis factor (ligand) superfamily, member 15

Rat HEK293 Cells
TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q8K3Y7.
TMPK-00631 DR3/TNFRSF25 Protein, Mouse, Recombinant (His)

TRAMP,TNFRSF12,WSL1,LARD,DR3,WSL,DDR3,TR3,TNFRSF25,APO3,WSL-...

Mouse HEK293 Cells
TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3.
TMPK-01378 IL-12B Protein, Cynomolgus, Recombinant (His)

CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS

Cynomolgus HEK293 Cells
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi...

重组蛋白

TL1A/TNFSF15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04645
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
Cat.No: TMPJ-00603
Species: Mouse
Expression System: E. coli
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01012
Species: Mouse
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01013
Species: Mouse
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-01011
Species: Mouse
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
Cat.No: TMPY-04978
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Human, Recombinant (His)
Cat.No: TMPY-05802
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00143
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04979
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00489
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03067
Species: Rat
Expression System: HEK293 Cells
DR3/TNFRSF25 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00631
Species: Mouse
Expression System: HEK293 Cells
IL-12B Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01378
Species: Cynomolgus
Expression System: HEK293 Cells
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