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Cat. No. | Product Name | Target | Signaling Pathways |
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T80559 |
Duvakitug
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Duvakitug为针对TNFSF15/TL1A的人源IgG1-λ2型单克隆抗体,在CHOK1SV细胞系的内源性谷氨酰胺合成酶(GS)阳性细胞中表达,适用于克罗恩病(Crohn's Disease, CD)研究。 | |||
T80560 |
Tulisokibart
PRA-023,PRA023 |
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Tulisokibart (PRA023)为人源化小鼠IgG1-κ型单克隆抗体,专一性靶向TNFSF15/TL1A。应用于炎症及纤维化疾病如克罗恩病(Crohn's Disease, CD)的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04645 |
TL1A/TNFSF15 Protein, Human, Recombinant (hFc)
TL1,tumor necrosis factor (ligand) superfamily, mem... |
Human | HEK293 Cells |
TL1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is A0A0U5JA19. | |||
TMPJ-00603 |
TL1A/TNFSF15 Protein, Mouse, Recombinant
TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V... |
Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ... | |||
TMPK-01012 |
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TL1,TNFSF15,VEGI,VEGI-251,TL1A,VE... |
Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8. | |||
TMPK-01013 |
TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
VEGI192A,TL1,VEGI-251,TL1A,TNFSF1... |
Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 48.8 kDa and the accession number is Q5UBV8. | |||
TMPK-01011 |
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)
TNFSF15,VEGI-251,TL1A,VEGI,TL1,VE... |
Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the accession number is Q5UBV8. | |||
TMPY-04978 |
TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
VEGI,VEGI192A,TL1,TL1A,tumor necr... |
Human | HEK293 Cells |
TL1A Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 48 kDa and the accession number is A0A0U5JA19. | |||
TMPY-05802 |
TL1A/TNFSF15 Protein, Human, Recombinant (His)
TL1A,VEGI,VEGI192A,tumor necrosis factor (... |
Human | HEK293 Cells |
TL1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is A0A0U5JA19. | |||
TMPK-00143 |
TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)
TL1A,TL1,TNFSF15,VEGI,VEGI192A,VE... |
Human | HEK293 Cells |
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight... | |||
TMPY-04979 |
TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
VEGI,tumor necrosis factor (ligand) superfamily, member 15,<... |
Human | HEK293 Cells |
TL1A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.1 kDa and the accession number is A0A0U5JA19. | |||
TMPK-00489 |
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TNFSF15,TNF superfamily member 15,TL1,VEGI192A,... |
Cynomolgus,Rhesus | HEK293 Cells |
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weigh... | |||
TMPY-03067 |
TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
tumor necrosis factor (ligand) superfamily, member 15 |
Rat | HEK293 Cells |
TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q8K3Y7. | |||
TMPK-00631 |
DR3/TNFRSF25 Protein, Mouse, Recombinant (His)
TRAMP,TNFRSF12,WSL1,LARD,DR3,WSL,DDR3,TR3,TNFRSF25,APO3,WSL-... |
Mouse | HEK293 Cells |
TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3. | |||
TMPK-01378 |
IL-12B Protein, Cynomolgus, Recombinant (His)
CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS |
Cynomolgus | HEK293 Cells |
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi... |