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Search Results for " tgfbetari "

Targets Recommended: TGF-beta/Smad

3

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9523	TGFβRI-IN-3	TGF-beta/Smad	Stem Cells
	TGFβRI-IN-3 抑制TGFβR1，IC50为 0.79 nM，是对 MAP4K4 的选择性2000 倍。TGFβRI-IN-3 是一种高选择性的 TGFβR1 抑制剂，在免疫肿瘤中具有潜在的应用。
T13137	TGFβRI-IN-1	TGF-beta/Smad	Stem Cells
	TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively ).
T13139	TP-008 TGFβRI-IN-2	Others	Others
	TGFβRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively).

化合物

Cat.No: T9523

Target: TGF-beta/Smad

Cat.No: T13137

Target: TGF-beta/Smad

Cat.No: T13139

Synonym: TGFβRI-IN-2

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi) tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,t...	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPK-00306	TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB1R1,LDS1A,AAT...	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is...
TMPJ-01178	TGFBR1 Protein, Mouse, Recombinant (hFc) ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1A,TGFbetaRI,TGFB1R...	Mouse	HEK293 Cells
	TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i...

重组蛋白

TGFBR1 Protein, Human, Recombinant (mFc & Avi)

Cat.No: TMPK-00305

Species: Human

Expression System: HEK293 Cells

TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated

Cat.No: TMPK-00306

Species: Human

Expression System: HEK293 Cells

TGFBR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01178

Species: Mouse

Expression System: HEK293 Cells

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