Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2513 |
VX-702
|
p38 MAPK; Autophagy | Autophagy; MAPK |
VX702 是一种高度特异性的 p38α MAPK 抑制剂,对 p38α 的选择性比 p38β 高 14 倍。它是一种小分子研究口服抗细胞因子疗法,用于治疗炎症性疾病,如类风湿性关节炎。 | |||
T40365 | T-2513 | ||
T-2513 is a potent and specific inhibitor of topoisomerase I. It acts by forming covalent bonds with the topoisomerase I-DNA complex, thereby enhancing its stability. This interaction disrupts the normal process of DNA replication and RNA synthesis, ultimately resulting in cellular apoptosis. |