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Search Results for " sumo2 "

Targets Recommended: E1/E2/E3 Enzyme

1

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16102	ML-792	E1/E2/E3 Enzyme	Ubiquitination
	ML-792 是特异性的小泛素样修饰物活化酶抑制剂。ML-792选择性抑制SAE/SUMO1和SAE/SUMO2，IC50分别为 3 和 11 nM，对 NAE/NEDD8 和 UAE/ubiquitin 抑制作用微弱，IC50分别为 32 μM 和 >100 μM。

化合物

Cat.No: T16102

Target: E1/E2/E3 Enzyme

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00486	SUMO2 Protein, Human, Recombinant (His) HSMT3,Ubiquitin-Like Protein SMT3A,SUMO-3,SMT3A,Sen...	Human	E. coli
	Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and l...
TMPJ-01022	SUMO3 Protein, Human, Recombinant (HEK293, His) SMT3 homolog 1,Smt3A,Small ubiquitin-related modifier 3,Ubiq...	Human	HEK293 Cells
	Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and/or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collect...
TMPJ-01021	SUMO3 Protein, Human, Recombinant SMT3H1,SMT3 Homolog 1,SUMO3,Small Ubiquitin-Related...	Human	E. coli
	SUMO3 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 KDa and the accession number is P55854.
TMPJ-01023	SUMO3 Protein, Human, Recombinant (E.coli, His) Ubiquitin-Like Protein SMT3B,SMT3H1,SUMO-3,Small Ub...	Human	E. coli
	SUMO3 Protein, Human, Recombinant (E.coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is P55854.
TMPJ-01336	SENP2 Protein, Human, Recombinant Sentrin/SUMO-specific protease SENP2,Axam<...	Human	E. coli
	SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
TMPJ-01324	UBA5 Protein, Human, Recombinant (His) Ubiquitin-like modifier-activating enzyme 5,UBE1DC1,UFM1-act...	Human	E. coli
	UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy th...
TMPH-00085	SIZ1 Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugat...

重组蛋白

SUMO2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00486

Species: Human

Expression System: E. coli

SUMO3 Protein, Human, Recombinant (HEK293, His)

Cat.No: TMPJ-01022

Species: Human

Expression System: HEK293 Cells

SUMO3 Protein, Human, Recombinant

Cat.No: TMPJ-01021

Species: Human

Expression System: E. coli

SUMO3 Protein, Human, Recombinant (E.coli, His)

Cat.No: TMPJ-01023

Species: Human

Expression System: E. coli

SENP2 Protein, Human, Recombinant

Cat.No: TMPJ-01336

Species: Human

Expression System: E. coli

UBA5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01324

Species: Human

Expression System: E. coli

SIZ1 Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00085

Species: Arabidopsis thaliana

Expression System: E. coli

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