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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13017 |
STL127705
Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione |
DNA-PK; Others | DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling |
STL127705 (Compound L) 是一种有效的 Ku 70/80 异二聚体蛋白抑制剂,抑制 Ku70/80-DNA 相互作用,IC50 为 3.5 μM。 它抑制 Ku 依赖性 DNA-PKCS 激酶的激活,IC50 为 2.5 μM。 | |||
T73443 |
STL1267
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STL1267 是一种有效的可穿过血脑屏障的REV-ERB 激动剂,对 REV-ERBα 的Ki 值为 0.16 µM。STL1267 没有表现出细胞毒性。STL1267 抑制 BMAL1 的基因表达。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01860 |
Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His)
SEDC,collagen, type II, alpha 1,COL11<... |
Human | HEK293 Cells |
COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of th... | |||
TMPY-01106 |
FSTL1 Protein, Human, Recombinant (His)
MIR198,FSL1,follistatin-like 1,FR... |
Human | HEK293 Cells |
FSTL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is Q12841-1. | |||
TMPJ-00191 |
FSTL1 Protein, Human, Recombinant
FRP,Follistatin-Related Protein 1,Follistatin-Like ... |
Human | E. coli |
Follistatin-Related Protein 1 (FSTL1) is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain, and one VWFC domain. Its functional significance in physiological and pathological processes is not completely understood. However, FSTL1 is thought to modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 maybe an autoantigen associated with rheumatoid arthritis. | |||
TMPY-00613 |
FSTL1 Protein, Mouse, Recombinant (hFc)
AW107808,AI316791,TSC-36,Fstl... |
Mouse | HEK293 Cells |
FSTL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 59.5 kDa and the accession number is Q62356. | |||
TMPY-04210 |
CSTL1 Protein, Human, Recombinant (hFc)
RCET11,cystatin-like 1,CTES1<... |
Human | HEK293 Cells |
CSTL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is AAI17397.1. | |||
TMPY-02556 |
FSTL1 Protein, Mouse, Recombinant (His)
AW107808,follistatin-like 1,Fstl,... |
Mouse | HEK293 Cells |
FSTL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.9 kDa and the accession number is Q62356. |