Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0187 |
SR-3677
|
ROCK; Autophagy | Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
SR-3677 是一种有效且特异性的 ROCK2 抑制剂,IC50值为3 nM。 | |||
T35828 |
SR 3677 dihydrochloride
|
||
Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively). Feng et al (2008) Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J.Med.Chem. 51 6642 PMID:18834107 |