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Cat. No.	Product Name	Target	Signaling Pathways
T13888	SLF	Others	Others
	SLF is a synthetic ligand for FK506-binding protein (FKBP)( with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12). SLF can be used in the synthesis of PROTAC.
T18061	KB02-SLF	Others	Others
	KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of protein degradation in biological systems. The compound SLF acts as a linker, binding to the ubiquitin E3 ligase ligand KB02, resulting in the formation of KB02-SLF[1].
T13914	SLF-amido-C2-COOH PROTAC FKBP12-binding moiety 1	Others	Others
	SLF-amido-C2-COOH is a synthetic ligand for FKBP (SLF), and can be used in the synthesis of PROTACs.
T73817	SLF TFA
	SLF TFA 是 FK506 结合蛋白 (FKBP) 的合成配体，对FKBP51的亲和力为 3.1 μM，对FKBP12的IC50为 2.6 μM，可用于合成PROTAC 分子。
T61112	SLF1081851	LPL Receptor	GPCR/G Protein
	SLF1081851 是一种 Spns2 抑制剂，抑制 S1P 释放 (IC50=1.93 μM)。SLF1081851 在发育和免疫系统中起关键作用。
T62851	SLF1081851 TFA
	SLF1081851 (TFA) 是一种 Spns2 抑制剂，抑制 S1P 释放的 IC50 值为 1.93 μM。SLF1081851 (TFA) 在发育和免疫系统中发挥着关键作用。
T74026	AUTAC2
	AUTAC2 是一种 FKBP12靶向自噬介导降解体 (AUTAC)。AUTAC2 包含一个 FBnG 和 SLF 部分，其中 SLF 与 FKBP12 非共价结合。
T39923	KB02-COOH KB02-COOH
	KB02-COOH is a synthetic fragment derived from ubiquitin E3 ligase ligand KB02, which possesses potential utility in the synthesis of PROTAC compounds. Notably, KB02-COOH can be employed in the generation of PROTAC constructs like KB02-JQ1 and KB02-SLF.
T18597	dFKBP-1	Others	Others
	dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
T80928	TSPO ligand-3	AUTACs	PROTAC
	TSPO ligand-3为AUTAC2的配体，其中AUTAC2包含p-氟苄基鸟嘌呤(FBnG)及FKBP合成配体(SLF)两部分，能在HeLa细胞中显著沉默FKBP12蛋白。

化合物

Cat.No: T13888

Target: Others

Cat.No: T18061

Target: Others

SLF-amido-C2-COOH

Cat.No: T13914

Synonym: PROTAC FKBP12-binding moiety 1

Target: Others

Cat.No: T73817

Cat.No: T61112

Target: LPL Receptor

SLF1081851 TFA

Cat.No: T62851

Cat.No: T74026

Cat.No: T39923

Synonym: KB02-COOH

Cat.No: T18597

Target: Others

Cat.No: T80928

Target: AUTACs

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