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Search Results for " sdc "

Targets Recommended: PPAR

4

抑制剂 & 化合物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38715	MSDC-0602K MSDC-0602K,Azemiglitazone potassium	PPAR	DNA Damage/DNA Repair; Metabolism
	MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both ...
T2607	MSDC 0160 CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others; IGF-1R; Mitochondrial Metabolism	Metabolism; Others; Tyrosine Kinase/Adaptors
	MSDC 0160 (CAY10415) 是一种线粒体丙酮酸载体(MPC) 的调节剂，也是调节噻唑烷二酮的线粒体靶标 (mTOT) 的胰岛素增敏剂。它是一种噻唑烷二酮 (TZD)，具有抗糖尿病和神经保护活性作用。它具有用于阿尔茨海默氏病的潜力。
T38961L	DP-1 hydrochloride DP-1 hydrochloride(1472616-61-7 Free base)	Drug Metabolite	Metabolism
	DP-1 hydrochloride是 SDC-TRAP-0063 的降解产物，是 Ganetespib 的一个片段。Ganetespib 是一种具有抗肿瘤活性的热休克蛋白 90 (HSP90) 抑制剂。
T38961	DP-1
	DP-1, a Ganetespib degradation product, represents a fragment derived from SDC-TRAP-0063. Ganetespib itself functions as an inhibitor of heat shock protein 90 (HSP90), exhibiting notable anti-tumor properties.

化合物

Cat.No: T38715

Synonym: MSDC-0602K,Azemiglitazone potassium

Target: PPAR

Cat.No: T2607

Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Target: Others, IGF-1R, Mitochondrial Metabolism

DP-1 hydrochloride

Cat.No: T38961L

Synonym: DP-1 hydrochloride(1472616-61-7 Free base)

Target: Drug Metabolite

Cat.No: T38961

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01630	Syndecan-1 Protein, Human, Recombinant (His) syndecan 1,CD138,syndecan,SYND1,SDC,Syndecan-1	Human	HEK293 Cells
	Syndecan-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P18827.
TMPJ-00487	SDC1 Protein, Human, Recombinant (hFc) CD138,SDC,SDC1,Syndecan-1,SYND1	Human	HEK293 Cells
	SDC1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is AAH08765.1.
TMPJ-00488	SDC1 Protein, Human, Recombinant (His) SDC,CD138,Syndecan-1,SYND1,SDC1	Human	HEK293 Cells
	SDC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 45-60 KDa and the accession number is AAH08765.1.
TMPK-00595	Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) Syndecan-1,CD138,SDC,SYND1,SDC1	Human	HEK293 Cells
	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25 kDa and the acc...
TMPK-01310	Syndecan-1 Protein, Rabbit, Recombinant (His) SDC1,SYND1,SDC,CD138,Syndecan 1	Rabbit	HEK293 Cells
	CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
TMPK-00593	Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated Syndecan-1,CD138,SDC1,SYND1,SDC	Human	HEK293 Cells
	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 ...
TMPK-01284	Syndecan-1 Protein, Cynomolgus, Recombinant (His) Syndecan-1,SYND1,SDC1,CD138,SDC	Cynomolgus	HEK293 Cells
	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 24.97 kDa and the access...
TMPK-00201	Syndecan-1 Protein, Mouse, Recombinant (hFc) Syndecan-1,CD138,SDC,SDC1,SYND1	Mouse	HEK293 Cells
	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51 kDa and the accession numb...
TMPK-00594	Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc) CD138,SDC1,SYND1,Syndecan-1,SDC	Human	HEK293 Cells
	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.6 kDa and the a...
TMPY-06859	Syndecan-1 Protein, Human, Recombinant (His & Avi) SYND1,syndecan,syndecan 1,Syndecan-1,CD138,SDC	Human	HEK293 Cells
	Syndecan-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.38 kDa and the accession number is NP_002988.3.
TMPY-06823	Syndecan-1 Protein, Human, Recombinant (hFc) syndecan,SYND1,SDC,syndecan 1,Syndecan-1,CD138	Human	HEK293 Cells
	Syndecan-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.85 kDa and the accession number is NP_002988.3.
TMPJ-00561	SDC2 Protein, Human, Recombinant (His) CD362,SDC2,HSPG,HSPG1,Syndecan-2,SYND2,Heparan Sulf...	Human	HEK293 Cells
	Syndecan-2 is a member of the Syndecans family comprised of type I transmembrane heparan sulfate proteoglycans (HSPG) that are involved in the regulation of many cellular processes. Four sub-types of mammalian Syndecans have been reported and among them. Syndecan-2 plays a role in the cancer development. It can affect the basal and chemotherapy-induced apoptosis in osteosarcoma. It can also suppress MMP2 activation, suppressing metastasis.
TMPY-01451	MESDC2 Protein, Human, Recombinant (His) MESD,mesoderm development candidate 2,BOCA	Human	HEK293 Cells
	MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside...

重组蛋白

Syndecan-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01630

Species: Human

Expression System: HEK293 Cells

SDC1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00487

Species: Human

Expression System: HEK293 Cells

SDC1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00488

Species: Human

Expression System: HEK293 Cells

Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)

Cat.No: TMPK-00595

Species: Human

Expression System: HEK293 Cells

Syndecan-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPK-01310

Species: Rabbit

Expression System: HEK293 Cells

Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00593

Species: Human

Expression System: HEK293 Cells

Syndecan-1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01284

Species: Cynomolgus

Expression System: HEK293 Cells

Syndecan-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00201

Species: Mouse

Expression System: HEK293 Cells

Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc)

Cat.No: TMPK-00594

Species: Human

Expression System: HEK293 Cells

Syndecan-1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPY-06859

Species: Human

Expression System: HEK293 Cells

Syndecan-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06823

Species: Human

Expression System: HEK293 Cells

SDC2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00561

Species: Human

Expression System: HEK293 Cells

MESDC2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01451

Species: Human

Expression System: HEK293 Cells

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