Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12841 |
SB-224289 hydrochloride
SB-224289A |
5-HT Receptor | GPCR/G Protein; Neuroscience |
SB-224289 hydrochloride (SB-224289A) 是一种选择性的 5-HT1B receptor 拮抗剂,具有抗焦虑作用。 | |||
T19690 |
SB 224289
SB224289,SB-224289 |
||
SB 224289 is a selective antagonist of 5-HT1B receptor with pKi of 8.2. It is a centrally active following oral administration in vivo. SB 224289 displays 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand |