Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69358 |
S101
|
||
S101 is an inhibitor of proliferating T-cells, rescuing mice from superantigen-induced shock. | |||
T3516 |
EDO-S101
Tinostamustine,Minomustine |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
EDO-S101 (Tinostamustine) 是一种泛 HDAC 抑制剂,IC50为 6 nM,对 HDAC1、HDAC2 和 HDAC3 的 IC50 值分别为 9、9 和 25 nM。 | |||
T70189 |
Navoximod phosphate
|
||
Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic. | |||
T5170 |
KHS101 hydrochloride
盐酸KHS101 |
FGFR; Microtubule Associated | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
KHS101 hydrochloride 能够选择性的诱导神经元分化表型,能够与转化酸性含螺旋蛋白发生相互作用。 | |||
T15715 |
LAS101057
|
Adenosine Receptor | GPCR/G Protein; Neuroscience |
LAS101057 是一种新型可口服且具有有效性和选择性的 A2B receptor 拮抗剂,可用于研究哮喘。 | |||
T70190 |
Tinostamustine HCl
|
||
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents. |