Cat. No. | Product Name | Target | Signaling Pathways |
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T22418 |
S-99
|
Others | Others |
S-99 是一种针对 ASK 的高纯度化学品,对免疫学、炎症、癌症研究非常重要。 | |||
T70584 | FLA-99 | ||
FLA-99 inhibits breakdown of inositol-1,4,5-triphosphate by inositol-1,4,5-triphosphate 5-phosphatase. | |||
T2012 |
Oclacitinib
PF-03394197 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Oclacitinib (PF-03394197) 是一种有效的选择性 JAKs 抑制剂,IC50 为 10-99 nM;不抑制一组 38 种非 JAK 激酶 (IC50 > 1000 nM)。 | |||
T66527 |
(S)-2-Amino-2-cyclopropylacetic acid
|
||
(S)-2-Amino-2-cyclopropylacetic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66527,CAS号为 49606-99-7。 | |||
T67239 |
Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II)
|
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Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67239,CAS号为 909389-99-7。 | |||
T37254 |
Rugulotrosin A
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Rugulotrosin A is an antibiotic originally isolated from Penicillium. It is active against the Gram-positive bacteria E. faecalis, B. cereus, B. subtilis, and S. aureus with 99% lethal dose (LD99) values of 1.6, 3.1, 5.5, and 200 μg/ml, respectively. Rugulotrosin A is inactive against Gram-negative bacteria. | |||
T36978 |
AS-99 TFA
|
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AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1]. AS-99 TFA is tested against a panel of 20 histone methyltransferases, including NSD1, NSD2, NSD3, and SETD2. NO significant inhibition is observed at 50 μM of AS-99 TFA on any of the tested... |