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Cat. No. | Product Name | Target | Signaling Pathways |
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T36408 |
Rhein-13C4
Rhein-13C4 |
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Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i... | |||
T35975 |
6,9-Dichloro-1,2,3,4-tetrahydroacridine
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6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3 1.Recanatini, M., Cavalli, A., Belluti, F., et al.SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylchol... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2997 |
Rhein
Rheinic Acid,Monorhein,大黄酸,NSC 38629,Rheic Acid,Rhubarb yellow |
Reactive Oxygen Species; Antibacterial; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Rhein (NSC 38629) 从蓼科大黄中提取的一种蒽醌类化合物,有抗炎、抗氧化、抗癌等作用。 | |||
TN2154 |
Rhein 8-Glucoside
大黄酸-8-葡糖苷,Rhein-8-glucoside,大黄酸 8-葡糖苷 |
Others | Others |
Rhein 8-Glucoside (Rhein-8-glucoside) 是一种蒽醌糖苷,存在于大黄(rhubarb) 中,显示出泻下活性。 | |||
T3827 |
Rhein-8-glucoside calcium
大黄酸-8-O-β-D-葡萄糖苷,Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt |
Phosphatase; Antibacterial | Metabolism; Microbiology/Virology |
Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt 是一种从 Saussurea lappa 根的 EtOH 提取物中,分离得到的蒽醌类 hPTP1B 抑制剂,IC50值为11.5 μM,具有抗菌作用。 | |||
TN3435 |
Aporheine
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Others | Others |
Aporheine is a natural product from Phellinus igniarius. | |||
T1273 |
Diacerein
双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein |
IL Receptor; Interleukin | Immunology/Inflammation |
Diacerein (Fisiodar) 是一种慢效具有白介素-1β 抑制效果的蒽醌类化合物。 | |||
TN2278 |
Torachrysone
决明柯酮 |
Antifection | Microbiology/Virology |
Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2- |