Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12480 |
Pipamperone
Floropipamide,McN-JR 3345,酰胺哌啶酮,R 3345 |
Others; Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience; Others |
Pipamperone (McN-JR 3345) 是5-HT2A 受体和D4受体的高亲和力拮抗剂,也是D2受体的低亲和力拮抗剂,pKi 分别为 8.2、8.0 和 6.7。 | |||
T28417 |
Pipamperone HCl
fluoropipamide,floropipamide hydrochloride,carpiperone,floropipamide,R4050,Pipamperone |
||
Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even hi |