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Cat. No. Product Name Target Signaling Pathways
T1776 Plerixafor

普乐沙福,JM3100,AMD 3100,AMD-3329

Virus Protease; HIV Protease; CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Plerixafor (AMD-3329) 是一种趋化因子受体拮抗剂,可阻断基质细胞衍生因子与细胞受体 CXCR4 的结合。它也是 CXCR7 的变构激动剂,是免疫刺激剂和造血干细胞动员剂,还抑制HIV-1和HIV-2的复制,EC50为 1-10 nM。
T1776L Plerixafor octahydrochloride

盐酸普乐沙福,JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl

Virus Protease; HIV Protease; CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Plerixafor octahydrochloride (JM3100 octahydrochloride) 是一种选择性的CXCR4拮抗剂,IC50为 44 nM。Plerixafor 是一种具有造血干细胞动员活性的双环霉素。
T36296 BIO5192 hydrate

BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2]. The combination of BIO5192 hydrate (1 mg/kg; i.v.) and Plerixafor (5 mg/kg; s.c.) exert an additive effect on progenitor mobilization[1].BIO5192 hydrate (30 mg/kg; s.c; bid; during days...

化合物

Plerixafor
Cat.No: T1776
Synonym: 普乐沙福,JM3100,AMD 3100,AMD-3329
Target: Virus Protease, HIV Protease, CXCR
Plerixafor octahydrochloride
Cat.No: T1776L
Synonym: 盐酸普乐沙福,JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl
Target: Virus Protease, HIV Protease, CXCR
BIO5192 hydrate
Cat.No: T36296
Synonym:
Target:
TargetMol Loading
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