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Cat. No. Product Name Target Signaling Pathways
T2386 Pirfenidone

S-7701,AMR-69,S-7701,AMR69,吡非尼酮

CCR; TGF-beta/Smad Immunology/Inflammation; Microbiology/Virology; Stem Cells
Pirfenidone (AMR69) 是一种抗纤维化剂,可减弱纤维细胞中CCL2和CCL12的产生。它可抑制细胞生长,并能降低人胶质瘤细胞系中的TGF-β2蛋白水平,具有抗炎活性。
T12485 Pirfenidone-d5

AMR69 D5,Pirfenidone D5

Others Others
Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.
T36618 Rupatadine

Rupatadine (UR-12592) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM(rabbit platelet membranes/guinea pig cerebellum membranes).IC50 value:Target: PAF/H1 antagonistin vitro: Rupatadine competitively inhibited histamine-induced guinea pig ileum contraction (pA2 = 9.29 +/- 0.06) without affecting contraction induced by ACh, serotonin or leukotriene D4 (LTD4). It also competitively inhibited PAF-induced platelet aggregation in washed rabbit platelets (WRP) (pA2 = 6.68 +/- 0.08) and in hu...

化合物

Pirfenidone
Cat.No: T2386
Synonym: S-7701,AMR-69,S-7701,AMR69,吡非尼酮
Target: CCR, TGF-beta/Smad
Pirfenidone-d5
Cat.No: T12485
Synonym: AMR69 D5,Pirfenidone D5
Target: Others
Rupatadine
Cat.No: T36618
Synonym:
Target:
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