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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T23153	Physostigmine hemisulfate	Others	Others
	cholinesterase inhibitor
T12446	Phenserine (-)-Eseroline phenylcarbamate,(-)-Phenserine	AChR	Neuroscience
	Phenserine is a derivative of Physostigmine and is annoncompetitive, long-acting and selective inhibitor of AChE.
T70607	Cymserine
	Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme.
T69029	Neostigmine
	Neostigmine is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
T69050	Neostigmine hydroxide
	Neostigmine hydroxide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
T73930	(-)-Eseroline fumarate
	(-)-Eseroline fumarate 是一种 AChE 抑制剂 Physostigmine 的代谢产物。(-)-Eseroline fumarate 引起癌细胞的乳酸脱氢酶 (LDH) 泄漏。(-)-Eseroline fumarate 还诱导神经元细胞释放腺嘌呤核苷酸和5-羟色胺 (5-HT)，从而诱导细胞死亡。(-)-Eseroline fumarate 抑制小鼠输精管和豚鼠回肠的电诱发抽搐。
T14614	Biperiden Hydrochloride KL 373 (Hydrochloride),盐酸比哌立登	Others	Others
	Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker and it is used for the adjunctive treatment of all forms of Parkinson's disease (postencephalitic, idiopathic, and arte

化合物

Physostigmine hemisulfate

Synonym: (-)-Eseroline phenylcarbamate,(-)-Phenserine

Neostigmine hydroxide

Cat.No: T69050

Synonym:

Target:

(-)-Eseroline fumarate

Cat.No: T73930

Synonym:

Target:

Biperiden Hydrochloride

Cat.No: T14614

Synonym: KL 373 (Hydrochloride),盐酸比哌立登

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T21438	Physostigmine Physostol,Antilirium,Eserine,毒扁豆碱,Esromiotin,Ezerin
	Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).
T0130	Physostigmine Salicylate 水杨酸依色林,水杨酸毒扁豆碱	AChR; AChE	Neuroscience
	Physostigmine salicylate 是一种可逆的乙酰胆碱酯酶抑制剂，也一种是抗胆碱能中毒的解毒剂。它可透过血脑屏障并刺激中枢胆碱能神经传递。它能逆转阿尔茨海默病转基因小鼠的记忆缺陷。