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Search Results for " psma "

27

抑制剂 & 化合物

1

天然产物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T28466	PSMA-11 HBED-CC-PSMA,Psma-hbed-CC,PSMA11
	PSMA-11 (HBED-CC-PSMA)通过与前列腺特异性膜抗原(PSMA)的细胞外结构域结合来检测前列腺癌的复发和转移。PSMA-11常被用作正电子发射断层扫描(PET)中用作表达PSMA 的肿瘤的示踪剂，通过静脉注射镓Ga 68标记的PSMA-11，Glu-urea-Lys(Ahx)分子靶向并结合表达PSMA 的肿瘤细胞。内化后，PSMA 表达的肿瘤细胞可在PET 成像中被检测到。
T40326	PSMA–DA1 PSMA–DA1
	PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.
T12573	Vipivotide tetraxetan PSMA-617	Others	Others
	Vipivotide tetraxetan (PSMA-617) 是一种高效的前列腺特异性膜抗原抑制剂，其Ki 值为 0.37 nM。
T39831	PSMA-ALB-56
	PSMA-ALB-56是通过结合谷氨酸脲基 psma 结合实体、DOTA 螯合剂和基于4-(对碘苯基)-片段或 p(tolyl)-片段的白蛋白结合剂而设计的一种 PSMA-targeting 放射性配体,具有抗肿瘤活性。
T69924	PSMA-1007
	PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.
T17233	Vipivotide tetraxetan Linker PSMA-617 Linker	Others	Others
	Vipivotide tetraxetan Linker (PSMA-617 Linker) is a noncleavable peptide linker utilized in the synthesis of Vipivotide tetraxetan (PSMA-617), a ligand instrumental in producing 177Lu-PSMA-617. This radioactive molecule is applied in the treatment of prostate cancer[1].
T78927	PSMA-IN-3
	PSMA-IN-3（compound 17）是一种高亲和力的新型PSMA抑制剂，IC50为13 nM。该化合物可作为开发18F标记的放射性配体的基础，用于前列腺癌PSMA的PET成像。
T78153	PSMA I&T	Others	Others
	PSMAI&T为高效的前列腺特异性膜抗原(PSMA)抑制剂，适用于前列腺癌(PCa)的单光子发射计算机断层扫描(SPECT)/计算机断层扫描(CT)显像及放射性核素研究。
T28467	PSMA617-TCMC TFA PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC
	PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.
T81361	PSMA-Val-Cit-PAB-MMAE
	PSMA-Val-Cit-PAB-MMAE是一种靶向前列腺特异性膜抗原（PSMA）的小分子化合物，用MMAE作为药效基团进行前列腺癌治疗。
T78412	Biotin-NH-PSMA-617
	Biotin-NH-PSMA-617为标记有生物素的PSMA-617小分子，专门针对前列腺特异性膜抗原（PSMA），后者为肿瘤细胞所特有表达。
T69923	Brigimadlin BI 907828
	Brigimadlin (BI 907828) 是一种 E3 泛素蛋白连接酶 MDM-2抑制剂。Brigimadlin 可作为抗肿瘤剂。
T31224	Piflufolastat DCFPYL	Epigenetic Reader Domain	Chromatin/Epigenetic
	Piflufolastat (DCFPYL) 是一种针对前列腺癌 PSMA 的 PET 显像剂。是一种含氟前列腺特异性膜抗原（PSMA）制剂。Piflufolastat 可用于制备 piflufolastat F 18 (DCFPyL F-18)。
T11122	DUPA(OtBu)-OH (S)-5-叔丁氧基-4-(3-((S)-1,5-二-叔丁氧基-1,5-二氧代-2-戊基)脲啶)-5-氧代戊酸	Others	Others
	DUPA(OtBu)-OH 是DUPA 前体。其中 DUPA 是传递 Docetaxel (DTX) 的靶向基序，可用于表达前列腺特异性膜抗原的前列腺肿瘤的研究。
T8925	Glu-urea-Lys
	Glu-urea-Lys 是一种靶向 PSMA 的分子支架，可用于研究前列腺特异性膜抗原的前列腺癌成像剂。
T9280	CS-0047390 (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate	Others	Others
	CS-0047390 ((S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate)又称 tert-Butyl-DCL，PSMA 抑制剂，是一种放射显影多肽试剂。
T19301	DUPA N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid	Others; Ligands for Target Protein for PROTAC	Others; PROTAC
	DUPA (N,N''-Carbonylbis[L-glutamic acid]) 是谷氨酸脲，在药物偶联中作为靶向部分，可选择靶向性地将细胞毒性药物递送到前列腺癌细胞。
T25814	MIP-1095 I-131 Iodine I 131 MIP-1095,131I-MIP-1095,Iodine I-131 MIP-1095,(131)I-MIP-1095
	MIP-1095 I-131 is a small molecule PSMA inhibitor.
T25295	Dcfpyl F-18 18F-DCFPyL
	Dcfpyl F-18 is used as a PET imaging agent for prostate-specific membrane antigen (PSMA).
T25293	DCFBC
	DCFBC is a low-molecular-weight radiotracer. It targets prostate-specific membrane antigen (PSMA).
T77130	Pasotuxizumab
	Pasotuxizumab (BAY 2010112) 是一种 PSMA 和 CD3双特异性的 T 细胞接合剂 (BiTE)。Pasotuxizumab 可结合CD3和 PSMA，对人CD3和 PSMA 的KD 分别为 9.4 nM 和 47.0 nM。Pasotuxizumab 可用于转移性去势抵抗性前列腺癌 (mCRPC) 的研究。
T62423	GCPII-IN-1 TFA
	GCPII-IN-1 TFA 是一种谷氨酸羧肽酶 II (GCPII; PSMA) 抑制剂支架 (Ki: 44.3 nM)。
T8925L	Glu-urea-Lys TFA(1025796-69-3 free base)	Others	Others
	Glu-urea-Lys TFA(1025796-69-3 free base)是一种 PSMA 抑制剂。
T78286	Rosopatamab HJ 591
	Rosopatamab (HJ 591) 是针对PSMA的人源化单克隆抗体，主要应用于癌症研究，尤其是前列腺癌。
T76955	Voxalatamab
	Voxalatamab (JNJ-63898081) 是一种可结合 PSMA 和 CD3的双特异性 IgG4抗体，具有抗癌活性，可用于前列腺癌研究。
T25294	DCFBC F-18 18F-DCFBC
	DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor imaging upon positron emission tomogra
T38420	GCPII-IN-1
	GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM).

化合物

Cat.No: T28466

Synonym: HBED-CC-PSMA,Psma-hbed-CC,PSMA11

Cat.No: T40326

Synonym: PSMA–DA1

Vipivotide tetraxetan

Cat.No: T12573

Synonym: PSMA-617

Target: Others

Cat.No: T39831

Cat.No: T69924

Vipivotide tetraxetan Linker

Cat.No: T17233

Synonym: PSMA-617 Linker

Target: Others

Cat.No: T78927

Cat.No: T78153

Target: Others

PSMA617-TCMC TFA

Cat.No: T28467

Synonym: PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC

PSMA-Val-Cit-PAB-MMAE

Cat.No: T81361

Biotin-NH-PSMA-617

Cat.No: T78412

Cat.No: T69923

Synonym: BI 907828

Cat.No: T31224

Synonym: DCFPYL

Target: Epigenetic Reader Domain

Cat.No: T11122

Synonym: (S)-5-叔丁氧基-4-(3-((S)-1,5-二-叔丁氧基-1,5-二氧代-2-戊基)脲啶)-5-氧代戊酸

Target: Others

Cat.No: T8925

Cat.No: T9280

Synonym: (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate

Target: Others

Cat.No: T19301

Synonym: N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid

Target: Others, Ligands for Target Protein for PROTAC

Cat.No: T25814

Synonym: Iodine I 131 MIP-1095,131I-MIP-1095,Iodine I-131 MIP-1095,(131)I-MIP-1095

Cat.No: T25295

Synonym: 18F-DCFPyL

Cat.No: T25293

Cat.No: T77130

Cat.No: T62423

Glu-urea-Lys TFA(1025796-69-3 free base)

Cat.No: T8925L

Target: Others

Cat.No: T78286

Synonym: HJ 591

Cat.No: T76955

Cat.No: T25294

Synonym: 18F-DCFBC

Cat.No: T38420

Cat. No.	Product Name	Target	Signaling Pathways
T4959	DL-Mannitol 甘露醇,Mannitol	Others	Others
	DL-Mannitol 是由 D-mannitol 与 L-mannitol 通过 L-mannono-1, Clactone 还原得到的。

天然产物

Cat.No: T4959

Synonym: 甘露醇,Mannitol

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00381	PSMA Protein, Human, Recombinant (His) FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (pr...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPY-06960	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated GCPII,FGCP,folate hydrolase (prostate-specific membrane anti...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 82.72 kDa and the accession number is NP_004467.1.
TMPK-00521	PSMA Protein, Cynomolgus, Recombinant (His) PSMA,FOLHNAALADase I,FGCP,GCPII,PSMAFGCP,N...	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 ...
TMPY-05269	PSMA Protein, Human, Recombinant (His), Biotinylated PSM,GCP2,folate hydrolase (prostate-specific membrane antige...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1.
TMPK-00370	PSMA Protein, Human, Recombinant (hFc) NAALAdase,FOLH1,FOLHNAALADase I,FGCP,mGCP,PSMAFGCP,...	Human	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Human, Recombinant (hFc) is expressed in HEK293 mamma...
TMPK-00371	PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAALAdase,FOL...	Mouse	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi...
TMPK-00522	PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAALADase I,...	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His...
TMPY-01390	PSMA Protein, Mouse, Recombinant (His) mopsm,folate hydrolase (prostate-specific membrane antigen) ...	Mouse	HEK293 Cells
	PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
TMPY-04078	PSMA3 Protein, Human, Recombinant (His) HC8,PSC3,proteasome (prosome, macropain) subunit, α type, 3,...	Human	E. coli
	PSMA3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.7 kDa and the accession number is AAH29402.1.

重组蛋白

PSMA Protein, Human, Recombinant (His)

Cat.No: TMPY-00381

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06960

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00521

Species: Cynomolgus

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05269

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00370

Species: Human

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

Cat.No: TMPK-00371

Species: Mouse

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Cat.No: TMPK-00522

Species: Cynomolgus

Expression System: HEK293 Cells

PSMA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01390

Species: Mouse

Expression System: HEK293 Cells

PSMA3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04078

Species: Human

Expression System: E. coli

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