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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7355 |
IC87201
|
Others; iGluR | Membrane transporter/Ion channel; Neuroscience; Others |
IC87201 是 PSD95-nNOS 相互作用的抑制剂,可抑制 nMDAR 诱导的一氧化氮和 cGMP 的形成,可用于缺血性中风和疼痛的研究。 | |||
T81899 |
LY836
|
iGluR | Membrane transporter/Ion channel; Neuroscience |
LY836是口服活性神经保护剂,有效阻断皮层神经元中PSD95-nNOS的关联,适用于缺血性脑卒中研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0883 |
Tramiprosate
Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸 |
Beta Amyloid; GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00652 |
PSD-95 Protein, Rat, Recombinant (His)
PSD95,SAP90,Disks large homolog 4,SAP-90,<... |
Rat | E. coli |
Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain,3 PDZ (DHR) domains and 1 SH3 domain. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. DLG4 is the be... |