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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78785 |
PRDX1-IN-1
|
Others | Others |
PRDX1-IN-1是一种针对PRDX1的选择性抑制剂,具有0.164 μM的IC50值。该化合物主要用于癌症相关研究,它能促进细胞内ROS积累,并通过诱导细胞凋亡来抑制肿瘤细胞的增殖、侵袭和迁移。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN5097 |
Tanshindiol C
|
LDL; Histone Methyltransferase | Chromatin/Epigenetic; Metabolism |
Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechani |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00441 |
PRDX1 Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
PRDX1 Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9JKY1. | |||
TMPH-00440 |
PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His)
|
Chinese hamster | E. coli |
PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPY-02372 |
Peroxiredoxin 1 Protein, Mouse, Recombinant (His)
PAG,OSF-3,OSF3,Paga,PRDX1,Tdpx2,PrxI,TDX2,... |
Mouse | E. coli |
Peroxiredoxin 1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.5 kDa and the accession number is P35700. | |||
TMPH-02153 |
Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. | |||
TMPJ-01098 |
PRDX4 Protein, Human, Recombinant (His)
Prx-IV,Thioredoxin-Dependent Peroxide Reductase A0372,PR... |
Human | E. coli |
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-... |