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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14280	AMPPD Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus	Others	Others
	AMPPD (Lumi-Phos Plus) 是一种超敏碱性磷酸酶底物，是 1,2-dioxo-cyclohexane 衍生物。
T28440	PPD 10558 PPD-10558,RBx10558,RBx-10558,PPD10558,RBx 10558
	PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.
T82900	Bemfivastatin hemicalcium PPD 10558 hemicalcium
	Bemfivastatin (PPD 10558) hemicalcium 作为口服HMG-CoA还原酶抑制剂，具备有效的降脂作用并能增强肝脏提取活性。该化合物的未观察到不良反应水平(NOAEL)在大鼠发育毒性研究中超过320 mg/kg/d，在家兔母体毒性及发育毒性研究中分别超过12.5 mg/kg/d和25 mg/kg/d。Bemfivastatin hemicalcium 适用于对他汀类药物不耐受且患有他汀相关性高胆固醇血症性肌痛的研究。
T83771	6-PPD Antioxidant 4020,N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine
	6-PPD是一种取代的p-苯二胺。它通过形成亚硝基自由基来清除臭氧。当6-PPD的浓度分别为0.022 mg/L和0.22 mg/L时，斑马鱼胚胎的孵化能力分别下降了25.6%和78.9%。6-PPD还会降低斑马鱼胚胎的活动能力和体长，并诱导发育畸形及氧化应激。含有6-PPD的配方已作为橡胶中的稳定剂添加物和抗臭氧剂使用。
T23179	PPDA	Others	Others
	Subtype-selective NMDA receptor antagonist
T79338	HPPD-IN-1
	HPPD-IN-1 (compound II-3)为一种有效的HPPD抑制剂，其对拟南芥HPPD (AtHPPD)的IC50为0.248 μM，表现出优于mesotrione的抑制效果（其IC50为0.283 μM）。此外，HPPD-IN-1对阔叶和单子叶杂草均展现出杰出的除草性能。
T22069	D-NMAPPD
	D-NMAPPD ((1R,2R)-B13) 是一种酸性神经酰胺酶 (acid ceramidase) 抑制剂。D-NMAPPD 通过增强神经酰胺的内源性产生来调节 NMDA 受体特性。D-NMAPPD 具有肠癌治疗的潜力。
T20104	C.I. 37545 NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes
	C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoazobenzene or aminoazotoluene, so tha

化合物

AMPPD

Cat.No: T14280

Synonym: Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus

Target: Others

PPD 10558

Cat.No: T28440

Synonym: PPD-10558,RBx10558,RBx-10558,PPD10558,RBx 10558

Target:

Bemfivastatin hemicalcium

Cat.No: T82900

Synonym: PPD 10558 hemicalcium

Target:

6-PPD

Cat.No: T83771

Synonym: Antioxidant 4020,N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine

Synonym: NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T78474	6PPD-Q 6PPD-Quinone	Endogenous Metabolite	Metabolism
	6PPD-Q（6PPD-醌）是一种可在人体尿液中检测到的内源性代谢产物，同时在环境中也广泛分布。

天然产物

6PPD-Q

Cat.No: T78474

Synonym: 6PPD-Quinone

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00938	4HPPD Protein, Human, Recombinant (His) PPD,4HPPD,HPD,4-Hydroxyphenylpyruvate Diox...	Human	E. coli
	4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in h...
TMPH-00422	Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc)	Clostridium symbiosum	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P22983.
TMPH-00515	PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)	Entamoeba histolytica	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis.