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Cat. No.	Product Name	Target	Signaling Pathways
T39516	Bocidelpar	PPAR	DNA Damage/DNA Repair; Metabolism
	Bocidelpar 是一种有效的过氧化物酶体增殖物激活受体 delta 调节剂，可改善杜兴肌营养不良肌肉细胞中的线粒体生物合成和功能。
T4408	Elafibranor GFT505	PPAR	DNA Damage/DNA Repair; Metabolism
	Elafibranor (GFT505) 是过氧化物酶体增殖物激活受体-α (PPAR-α) 和过氧化物酶体增殖物激活受体-δ (PPAR-δ) 的激动剂，EC50 值分别为 45 和 175 nM。
T15567	Imiglitazar TAK-559	PPAR	DNA Damage/DNA Repair; Metabolism
	Imiglitazar (TAK559)是有效的 PPAR-β/δ受体激动剂，具有降血糖作用。
T15575	Indeglitazar PPM 204	PPAR	DNA Damage/DNA Repair; Metabolism
	Indeglitazar (PPM 204) 是 PPAR 的泛激动剂，包括亚型 alpha (α)、delta (δ) 和 gamma (γ)。
T4628	Seladelpar MBX 8025	PPAR	DNA Damage/DNA Repair; Metabolism
	Seladelpar (MBX 8025) 是一种有效的，具有口服活性的，特异性PPAR-δ激动剂，EC50为 2 nM。
T12528	Pparδ agonist 1	Others	Others
	Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).
T26182	Seladelpar lysine MBX-8025 lysine dihydrate,MBX-8025 Lysine,MBX 8025 Lysine MBX8025 Lysine
	Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).
T70886	PT-S58
	PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ/δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.
T37829	CAY10573
	The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound ros...
T79454	Anti-NASH agent 1	PPAR	DNA Damage/DNA Repair; Metabolism
	Anti-NASH agent 1 (compound 3d)，Elafibranor衍生物，高效PPAR-α/δ激动剂，针对非酒精性脂肪性肝炎（NASH）。以3-10 mg/kg剂量，连续4周处理，能显著改善蛋氨酸胆碱缺乏（MCD）诱导的NASH小鼠高脂血症、肝脏脂肪变性及炎症状况，展现出低肝毒性和良好肝脏保护效能。
T35813	CAY10592
	Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARδ receptor agonists, though relatively obscure, have recently been reported to elevate high-density lipoprotein (HDL) cholesterol and lower plasma triglyceride (TG) levels in obese insulin resistant rhesus monkeys. CAY10592 is a full PPARδ agonist (EC50 = 30 nM) ...