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Search Results for " pn1 "

Targets Recommended: PDE

2

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13193	TPN171	PDE	Metabolism
	TPN171是一种有效的 PDE5抑制剂，对 PDE5具有亚纳摩尔效价，对 PDE5比对 PDE6具有良好的选择性，具有治疗肺动脉高压(PAH)的潜力。在动物模型中，TPN171被证明具有比西地那非更持久的作用，为临床使用每日一次口服提供了基础。
T16795	Rpn11-IN-1 Capzimin intermediate	Others	Others
	Rpn11-IN-1 is an effective and selective inhibitor of proteasome subunit Rpn11 (IC50: 390 nM).

化合物

Cat.No: T13193

Target: PDE

Cat.No: T16795

Synonym: Capzimin intermediate

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00796	Serpin E2 Protein, Human, Recombinant (His) PN-1,PI-7,Protease nexin 1,PI7,GD...	Human	HEK293 Cells
	Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown tha...
TMPJ-01083	Serpin E2 Protein, Mouse, Recombinant (His) Pi7,Protease nexin I,Spi4,Pn1,Serine prote...	Mouse	HEK293 Cells
	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Ser...
TMPH-01029	CAPN1 Protein, Human, Recombinant (His) CANPL1,CAPN1,Calpain-1 c...	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. CAPN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.9 kDa and the accession number is P07384.
TMPK-00016	Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated Hsp10,Chaperonin 10,HSPE1,GROES,E...	Human,Mouse,Goat	E. coli
	Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell proliferation. Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription. Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated is expressed in E. coli expre...
TMPK-00015	Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi) GROES,Hsp10,Chaperonin 10,HSPE1,E...	Human,Mouse,Goat	E. coli
	Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell proliferation. Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription. Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi) is expressed in E. coli expression system w...
TMPY-04804	Cpn10/HSPE1 Protein, Human, Recombinant (His) GROES,heat shock 10kDa protein 1,EPF,HSP	Human	E. coli
	Cpn10/HSPE1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 13.2 kDa and the accession number is A0A384N6A4.
TMPH-02557	CAPN1 Protein, Mouse, Recombinant (His) CANP 1,Calpain-1 catalytic subunit,muCANP,...	Mouse	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His-410'.
TMPY-03486	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) PTPG1,protein tyrosine phosphatase, non-receptor ty...	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.4 kDa and the accession number is AAA36529.1.
TMPH-01030	CAPN14 Protein, Human, Recombinant (His & Myc) Calpain-14,Calcium-activated neutral proteinase	Human	Baculovirus Insect Cells
	Calcium-regulated non-lysosomal thiol-protease. CAPN14 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 78.6 kDa and the accession number is A8MX76.
TMPH-01615	OPN1LW Protein, Human, Recombinant (His)	Human	E. coli
	Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. OPN1LW Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P04000.
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
TMPY-03548	PTPN12 Protein, Human, Recombinant protein tyrosine phosphatase, non-receptor type 12,...	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.

重组蛋白

Serpin E2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00796

Species: Human

Expression System: HEK293 Cells

Serpin E2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01083

Species: Mouse

Expression System: HEK293 Cells

CAPN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01029

Species: Human

Expression System: E. coli

Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00016

Species: Human,Mouse,Goat

Expression System: E. coli

Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi)

Cat.No: TMPK-00015

Species: Human,Mouse,Goat

Expression System: E. coli

Cpn10/HSPE1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04804

Species: Human

Expression System: E. coli

CAPN1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02557

Species: Mouse

Expression System: E. coli

PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST)

Cat.No: TMPY-03486

Species: Human

Expression System: Baculovirus Insect Cells

CAPN14 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01030

Species: Human

Expression System: Baculovirus Insect Cells

OPN1LW Protein, Human, Recombinant (His)

Cat.No: TMPH-01615

Species: Human

Expression System: E. coli

PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

Cat.No: TMPH-02277

Species: Human

Expression System: E. coli

PTPN12 Protein, Human, Recombinant

Cat.No: TMPY-03548

Species: Human

Expression System: Baculovirus Insect Cells

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