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Cat. No. Product Name Target Signaling Pathways
T2528 Latanoprost

Xalatan,PHXA41,拉坦前列腺素,拉坦前列素

GPR; Prostaglandin Receptor; RAR/RXR  Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
Latanoprost (Xalatan) 是前列腺素 F2α 类似物,是一种前列腺素受体激动剂,能够降低眼内压。
T37931 15(S)-Latanoprost

15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-Latanoprost is a potential impurity in most commercial preparations of the ...
T37213 5-trans Latanoprost

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. Fr...
T37214 5-trans Latanoprost (free acid)

Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent than latanoprost as a ligand for the human recombinant FP receptor. 5-trans Latanoprost (free acid) is an isomer of latanoprost (free acid) wherein the double bond between carbons 5 and 6 has been changed from ci...

化合物

Latanoprost
Cat.No: T2528
Synonym: Xalatan,PHXA41,拉坦前列腺素,拉坦前列素
Target: GPR, Prostaglandin Receptor, RAR/RXR 
15(S)-Latanoprost
Cat.No: T37931
Synonym:
Target:
5-trans Latanoprost
Cat.No: T37213
Synonym:
Target:
5-trans Latanoprost (free acid)
Cat.No: T37214
Synonym:
Target:
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