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7

抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T26376 11-deoxy-PGF2a

11-deoxyPGF2a,11-deoxy PGF2a

11-deoxy-PGF2a, a selective activator of TREK-2 channels, stimulates DRG c-fiber nociceptor K2P currents and limits calcium influx.
T25168 Boc-ypgflt(O-tbu)

Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu)

Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.
T83687 Mca-RPPGFSAFK(Dnp)-OH TFA

(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(2,4-dinitrophenyl)-OH

Mca-RPPGFSAFK(Dnp)-OH 是 endothelin-converting enzyme-1 (ECE-1) 的一种荧光底物。当 ECE-1 切割该底物时,会释放 7-methoxycoumarin-4-acetyl (Mca),其荧光可以用来量化 ECE-1 的活性。Mca 的激发/发射峰值分别为 328/420 nm。
T5148 Atosiban acetate

RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班

Oxytocin Receptor; Vasopressin Receptor Endocrinology/Hormones; GPCR/G Protein
Atosiban acetate (RW22164) 是一种脱氨基催产素类似物,是一种九肽,也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂,可用于自发早产的研究。
T4996 Atosiban

阿托西班,RWJ22164,RW22164

Oxytocin Receptor; Vasopressin Receptor Endocrinology/Hormones; GPCR/G Protein
Atosiban (RW22164) 是一种脱氨基催产素类似物,是一种九肽,也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂,可用于自发早产的研究。
T21752 AL 8810

AL-8810 是 PGF2α的一种 11β- 氟类似物,对PGF2α受体(FP 受体) 具有选择性拮抗作用。
T31372 Delprostenate

A 2774,A2774,A-2774

Delprostenate is similar to PGF(2alpha), a naturally occurring prostaglandin used in medical labor induction and abortion drugs.

化合物

11-deoxy-PGF2a
Cat.No: T26376
Synonym: 11-deoxyPGF2a,11-deoxy PGF2a
Target:
Boc-ypgflt(O-tbu)
Cat.No: T25168
Synonym: Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu)
Target:
Mca-RPPGFSAFK(Dnp)-OH TFA
Cat.No: T83687
Synonym: (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(2,4-dinitrophenyl)-OH
Target:
Atosiban acetate
Cat.No: T5148
Synonym: RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班
Target: Oxytocin Receptor, Vasopressin Receptor
Atosiban
Cat.No: T4996
Synonym: 阿托西班,RWJ22164,RW22164
Target: Oxytocin Receptor, Vasopressin Receptor
AL 8810
Cat.No: T21752
Synonym:
Target:
Delprostenate
Cat.No: T31372
Synonym: A 2774,A2774,A-2774
Target:
Cat. No. Product Name Species Expression System
TMPK-00893 PGF Protein, Human, Recombinant (hFc)

PlGF,SHGC-10760,PGFL,PGF,D12S1900,PlGF-2

Human HEK293 Cells
Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized strategies to target inflammation-mediated angiogenesis may help to increase efficacy and reduce non-responders in the treatment of wet AMD patients.
TMPY-03466 PLGF/PGF Protein, Mouse, Recombinant

placental growth factor,Plgf,PIGF,AI854365

Mouse HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.6 kDa and the accession number is P49764.
TMPJ-00987 PLGF/PGF Protein, Mouse, Recombinant (His)

Plgf,PlGF-2,PGFL,PGF,SHGC-10760,D12S1900,P...

Mouse HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPJ-00054 PLGF-2 Protein, Human, Recombinant (His)

PlGF-2,PlGF2,PlGF,PGF,PGFL

Human HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF‑1), 152 (PlGF‑2), and 203 (PlGF‑3) amino acids (aa) respectively. PlGF is mainly found as a variably glycosylated, secreted, 55 ‑ 60 kDa disulfide linked homodimer.The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key ...
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc)

placental growth factor,D12S1900,PLGF,SHGC-10760,PGF

Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-02423 PLGF/PGF Protein, Mouse, Recombinant (hFc)

Plgf,placental growth factor,PIGF,AI854365

Mouse HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is P49764.
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascular perme...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPK-00454 VEGFR2/KDR Protein, Human, Recombinant (His & Avi)

VEGFR-21,Ly73,KRD1,VEGFR2,CD309,FLK1,VEGFR,KDR

Human HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-H...
TMPK-00645 VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)

KRD1,VEGFR2,FLK1,CD309,Ly73,VEGFR,VEGFR-21,KDR

Rhesus HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with ...
TMPJ-00355 Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated

CD304,VEGF165R,NRP1,NRPNP1,BDCA4

Human HEK293 Cells
Neuropilin-1 (Npn-1, previously neuropilin; also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identified. Neuropilin-1 binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds ...

重组蛋白

PGF Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00893
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant
Cat.No: TMPY-03466
Species: Mouse
Expression System: HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00987
Species: Mouse
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
PLGF-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00054
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00276
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02423
Species: Mouse
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00454
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00645
Species: Rhesus
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated
Cat.No: TMPJ-00355
Species: Human
Expression System: HEK293 Cells
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