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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16947 |
SU16f
3-substituted indolin-2-one 16f,SU-16F,SU 16F |
PDGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
SU16f (3-substituted indolin-2-one 16f) 是一种有效的,选择性 PDGFRβ 抑制剂,对 PDGFRβ,PDGFR1,PDGFR2 的 IC50 分别为 10 nM,140 nM,2.29 μM。SU16f 抑制 PDGFRβ 受体从而可以阻断胃癌来源的间充质干细胞 (GC-MSC) 条件培养基在胃癌细胞增殖和迁移中的促进作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01139 |
PDGFRA Protein, Human, Recombinant (His)
PDGFR-2,CD140A,RHEPDGFRA,platelet... |
Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1. | |||
TMPY-00900 |
PDGFRA Protein, Human, Recombinant (hFc)
PDGFR-2,platelet-derived growth factor rec... |
Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is P16234-1. | |||
TMPK-00419 |
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
RHEPDGFRA,PDGFR-2,CD140A,PDGF... |
Human | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The p... | |||
TMPY-05608 |
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
platelet-derived growth factor receptor, α polypeptide,RHE |
Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is P16234-1. | |||
TMPK-00943 |
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R α/PDGFRA Protein, Cynomolgus, Recombinant (H... |
Cynomolgus | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predic... | |||
TMPK-00420 |
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
RHEPDGFRA,PDGFRA,PDGF R α/PDGFRA ... |
Human | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-... | |||
TMPK-00481 |
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta,PDGFRB,PDGFR-2,PDGF-R... |
Cynomolgus | HEK293 Cells |
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target. | |||
TMPK-00422 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGFR-2,PDGF R β/CD140b,PDGFR1,CD... |
Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPK-00421 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
PDGFR1,CD140B,PDGFR-2,PDGF R β/CD... |
Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPK-01050 |
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
JTK12,PDGF R β,PDGFR-β,PDGFR,... |
Canine | HEK293 Cells |
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3. |